Results 61 to 70 of about 5,089 (179)

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

The effect of the disulfideisomerase domain containing protein in the defense against polyhexamethylene biguanide of highly tolerant Acanthamoeba at the trophozoite stage

International Journal for Parasitology: Drugs and Drug Resistance, 2016
Acanthamoeba castellanii is a free-living protozoan pathogen capable of causing a blinding keratitis and fatal granulomatous encephalitis. Current treatment generally involves an hourly application of polyhexamethylene biguanide (PHMB) over a period of ...
Fu-Chin Huang, Tao-Shen Liu, Sung-Chou Li, Min-Hsiu Shih, Jyh-Wei Shin, Wei-Chen Lin   +5 more
doaj   +1 more source

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, Volume 15, Issue 15, 17 April 2026.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

IgE‐mediated chlorhexidine allergy—Cross‐reactivity with other biguanide disinfectants [PDF]

, 2020
: Background Chlorhexidine (CHX) is a widely utilized disinfectant that can cause IgE-mediated urticaria/anaphylaxis. The cross-reactivity of patients with IgE-mediated CHX allergy with other disinfectants, which share structural similarities with CHX ...
Suran L. Fernando, Buenter, Antonia, Gupta, Nisha, Mueller-Wirth, Nicole, Antonia Buenter, Hausmann, Oliver, Didier G. Ebo, Fernando, Suran L., Glatz, Martin, Nicole Mueller‐Wirth, Martin Glatz, Ebo, Didier G., Werner J. Pichler, Ebo, Didier, Helbling, Arthur, Mueller‐Wirth, Nicole, Oliver Hausmann, Lukas Jörg, David Spoerl, Spoerl, David, Nisha Gupta, Arthur Helbling, Jorg, Lukas, Pichler, Werner J.   +23 more
core   +1 more source

Irrigation in Endodontics: Polyhexanide Is a Promising Antibacterial Polymer in Root Canal Treatment

Dentistry Journal, 2023
Background:chronic apical periodontitis is a common pathology in dentistry, especially in endodontics. It is necessary to systematize data concerning commonly used irrigation solutions.
Zurab Khabadze, Yulia Generalova, Alena Kulikova, Irina Podoprigora, Saida Abdulkerimova, Yusup Bakaev, Mariya Makeeva, Marina Dashtieva, Mariya Balashova, Fakhri Gadzhiev, Oleg Mordanov, Adam Umarov, Haddad Tarik, Andrei Zoryan, Amina Karnaeva, Yakup Rakhmanov   +15 more
doaj   +1 more source

Management and Outcomes of Diabetic Foot Complications Requiring Surgical Intervention at a Sudanese First‐Level Hospital: A Prospective Clinical Audit

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Diabetic foot complications, encompassing ulcers, abscesses, and tissue necrosis, are common and serious complications of diabetes mellitus that can significantly impact quality of life and potentially lead to amputation, particularly in the presence of risk factors and inadequate care.
Ibrahim Abusufian Elkabashi Dafallah, Duha Elfatih Elamin Awadalla, Ahmed Fathalrahman Zainalabdin, Hammam Mohamed Awadelkareem Badawi, Mohammed Elfatih Elamin Awadalla, Nazik Mahmoud Abdelaal Abeldaifa, Ahmed Mohamed Awadelkareem Badawi   +6 more
wiley   +1 more source

In Vitro and In Vivo Comparison of a Novel Antimicrobial Wound Hydrogel With Commercial Wound Treatments: Antimicrobial, Antibiofilm and Biocompatibility Assessment

International Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Antimicrobial resistance (AMR) and biofilm formation significantly hinder chronic wound management, necessitating safer and more effective therapeutic options. This study evaluates the antimicrobial, antibiofilm, cytocompatibility and anti‐inflammatory properties of a novel antimicrobial hydrogel Formulation (#1) compared with commercially ...
Melika Moradi, Ali Pormohammad, Charline Luong, Raymond J. Turner   +3 more
wiley   +1 more source

Type I collagen matrix plus polyhexamethylene biguanide antimicrobial for the treatment of cutaneous wounds.

, 2020
Aim: Determine the effectiveness of purified native type I collagen matrix plus polyhexamethylene biguanide antimicrobial (PCMP) on cutaneous wounds. Materials & methods: A prospective cohort study of 307 patients (67 venous leg ulcers, 62 diabetic foot ...
Bain, Michael, Morse, Keith, Wendling, Santina, Sabolinski, Michael L, Koullias, George J   +4 more
core   +1 more source

Polyhexanide (PHMB) – properties and applications in medicine

European Journal of Biological Research, 2020
Polyhexamethylene biguanide (PHMB) is one of the many antiseptics available in the medicine. It stands out from the others with its numerous advantages.
Patrycja Szkołuda, Tomasz M. Karpiński
doaj  

Implementing Wound Hygiene in the Italian Healthcare Context: Expert Recommendations for the Management of Venous Leg Ulcers

International Wound Journal, Volume 23, Issue 3, March 2026.
ABSTRACT The ‘Wound Hygiene Italia’ project was designed to provide expert‐driven recommendations for the assessment, management and monitoring of venous leg ulcers, tailored to diverse settings of care (hospital, ambulatory and home care). The recommendations, developed by a multidisciplinary panel, emphasise the implementation of the Wound Hygiene ...
Alessandro Scalise, Franco Bassetto, Diego Ceci, Guido Ciprandi, Deborah Cesura Granara, Barbara De Angelis, Ciro Falasconi, Domitilla Foghetti, Francesco Giacinto, Alessandro Greco, Filippo Magnoni, Marco Marchelli, Giuseppe Nebbioso, Battistino Paggi, Giovanni Papa, Francesco Petrella, Salvatore Piazza, Marco Romanelli, Elia Ricci, Sara Sandroni   +19 more
wiley   +1 more source