Effect of polyhexamethylene biguanide-coated central venous catheters on bacterial colonization in cancer patients undergoing abdominal surgery: a randomized controlled trial [PDF]
Frontiers in MedicineBackgroundCentral venous catheters (CVCs) are widely used in critically ill patients, including cancer patients, but are associated with complications such as catheter-related bloodstream infections (CRBSIs).
Jun Dong +5 more
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Ouabain, ATPase inhibitor, potentially enhances the effect of polyhexamethylene biguanide on Acanthamoeba castellanii [PDF]
International Journal for Parasitology: Drugs and Drug ResistanceAcanthamoeba, a free-living amoeba, is commonly found in various natural environments, such as rivers and soil, as well as in public baths, swimming pools, and sewers.
Kuang-Yi Shih +3 more
doaj +2 more sources
Double-Biguanide Therapy for Resistant Acanthamoeba Keratitis
Case Reports in Ophthalmology, 2011 Aims: To report the clinical and diagnostic findings of a patient with Acanthamoeba keratitis resistant to both polyhexamethylene biguanide (PHMB)-hexamidine and chlorhexidine-hexamidine treatment.
Giulio Ferrari +2 more
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Corneal Penetration of Polyhexamethylene Biguanide and Chlorhexidine Digluconate
Journal of Clinical & Experimental Ophthalmology, 2015 Objective: Cationic antiseptics, such as polyhexamethylene biguanide (PHMB) and chlorhexidine digluconate (CHG), are widely used for the topical treatment of Acanthamoeba keratitis. The aim of this study was to investigate the corneal penetration of PHMB and CHG topically administered as eye drops and to study the effect of PHMB and CHG on the ...
Vontobel, S. F. +5 more
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Effect of Polyhexamethylene Biguanide in Combination with Undecylenamidopropyl Betaine or PslG on Biofilm Clearance [PDF]
International Journal of Molecular Sciences, 2021 Di Wang
exaly +2 more sources
Efficacy of 0.2% povidone-iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures. [PDF]
Vet OphthalmolAbstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Farkas A +4 more
europepmc +2 more sources
Microorganisms, 2022 In recent years, a rise in the number of contact lens users in the UK and worldwide coincided with an increased incidence of microbial keratitis. The aim of this study was to investigate the antimicrobial activities of polyhexamethylene guanidine (PHMG),
Dharanga Ratnayake +3 more
doaj +1 more source
Membranes, 2023 Wound infection is a common complication of chronic wounds. It can impair healing, which may not occur without external help. Antimicrobial dressings (AMDs) are a type of external help to infected chronic wounds.
Luís M. Vaz +3 more
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Polyhexanide as a new antiseptic composition for a dentist
Эндодонтия Today, 2021 Aim. To assess systematically the available scientific evidence about clinical response of using polyhexanide as an antiseptic agent in medicine and dentistry.
Z. S. Khabadze +5 more
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Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review
Membranes, 2022 The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
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