Polyhexamethylene Biguanide Nanoparticles Inhibit Biofilm Formation by Mastitis-Causing Staphylococcus aureus [PDF]
Veterinary SciencesStaphylococcus aureus is a mastitis pathogen that compromises cow health and causes significant economic losses in the dairy industry. High antimicrobial resistance and biofilm formation by S. aureus limit the efficacy of conventional treatments.
Renata de Freitas Leite +9 more
doaj +2 more sources
Raman microspectroscopy analysis in the treatment of acanthamoeba keratitis. [PDF]
PLoS ONE, 2013 Acanthamoeba keratitis is a rare but serious corneal disease, often observed in contact lens wearers. Clinical treatment of infected patients frequently involves the use of polyhexamethylene biguanide (PHMB), a polymer used as a disinfectant and ...
Giulia Rusciano +7 more
doaj +8 more sources
Management of Severe Pediatric Lower Lip Defect After Canine Bite with Polyhexamethylene Biguanide (PHMB), Full-Thickness Skin Graft (FTSG) and Compression Foam: A Case Report [PDF]
ChildrenIntroduction: Pediatric lower-lip dog bite injuries are challenging due to contamination, tissue loss, and the need to maintain function, appearance, and psychological well-being.
Aba Lőrincz +6 more
doaj +2 more sources
The dltC gene contributes to polyhexamethylene biguanide resistance in Staphylococcus aureus [PDF]
Frontiers in MicrobiologyAs the efficacy of conventional antibiotics continues to decline due to antibiotic resistance, there is an urgent need for alternative antimicrobial strategies.
Chenyang Guo +10 more
doaj +2 more sources
Determination of Polyhexamethylene Biguanide Utilizing a Glucose Oxidase Enzymatic Reaction
Analytical Sciences, 2019 Polyhexamethylene biguanide (PHMB) is a cationic disinfectant widely used for personal-care products and for sanitizers in swimming pools. This paper describes a promotion effect of PHMB on a glucose oxidase (GOx) enzymatic reaction with ferricyanide ion and its analytical application. The promotion effect arose from a polyion complex formation between
Kohei Uematsu +2 more
openalex +4 more sources
Determination of Polyhexamethylene Biguanide Hydrochloride Using a Lactone-Rhodamine B-Based Fluorescence Optode [PDF]
Molecules, 2020 A new determination method for polyhexamethylene biguanide hydrochloride (PHMB) using a lactone-rhodamine B (L-RB) based fluorescence optode has been developed.
Akane Funaki +3 more
doaj +2 more sources
Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus [PDF]
Polymers (Basel), 2018 The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is limited.
Chivu, A +3 more
core +4 more sources
Surface-Modified Carboxylated Cellulose Nanofiber Hydrogels for Prolonged Release of Polyhexamethylene Biguanide Hydrochloride (PHMB) for Antimicrobial Applications. [PDF]
Polymers (Basel), 2023 O-Chongpian P +6 more
europepmc +3 more sources
Effect of polyhexamethylene biguanide-coated central venous catheters on bacterial colonization in cancer patients undergoing abdominal surgery: a randomized controlled trial [PDF]
Frontiers in MedicineBackgroundCentral venous catheters (CVCs) are widely used in critically ill patients, including cancer patients, but are associated with complications such as catheter-related bloodstream infections (CRBSIs).
Jun Dong +5 more
doaj +2 more sources
Bactericidal Effect and Mechanism of Polyhexamethylene Biguanide (PHMB) on Pathogenic Bacteria in Marine Aquaculture [PDF]
BiologyGuanidine disinfectants are cationic polymers recognized for their effective sterilization properties and their ability to prevent bacterial resistance.
Lanting Wu +9 more
doaj +2 more sources