Results 1 to 10 of about 235 (80)

Antiseptic Chitosan-Poly(hexamethylene) Biguanide Hydrogel for the Treatment of Infectious Wounds [PDF]

Journal of Functional Biomaterials, 2023
Topical wound infections create the ideal conditions for microbial colonization and growth in terms of moisture, temperature, and nutrients. When they are not protected, numerous types of bacteria from the internal microbiota and the external environment
Irine Rose Antony, Aathira Pradeep, Anoop Vasudevan Pillai, Riju Ramachandran Menon, Vasudevan Anil Kumar, Rangasamy Jayakumar   +5 more
doaj   +4 more sources

3D-Printed PLDLA–TMC/PEG 400 Vascular Scaffolds with a Poly(hexamethylene Biguanide) Antibacterial Coating [PDF]

Pharmaceutics
Background: Synthetic vascular scaffolds often exhibit limited mechanical performance and low hydrophilicity, which compromise early vascular integration and increase susceptibility to bacterial colonization.
Monique M. Munhoz, Flavia Pedrini, Cecilia T. de Barros, Maria Eduarda Dias, Camilla Fanelli, Irene L. Noronha, Daniel Komatsu, Eliana A. de R. Duek, Moema de A. Hausen   +8 more
doaj   +4 more sources

Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings [PDF]

Membranes, 2023
Wound infection is a common complication of chronic wounds. It can impair healing, which may not occur without external help. Antimicrobial dressings (AMDs) are a type of external help to infected chronic wounds.
Luís M. Vaz, Rita Branco, Paula V. Morais, António Jorge Guiomar   +3 more
doaj   +2 more sources

Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review [PDF]

Membranes, 2022
The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
doaj   +2 more sources

Effect of poly-hexamethylene biguanide hydrochloride (PHMB) treated non-sterile medical gloves upon the transmission of Streptococcus pyogenes, carbapenem-resistant E. coli, MRSA and Klebsiella pneumoniae from contact surfaces [PDF]

BMC Infectious Diseases, 2017
Background Reduction of accidental contamination of the near-patient environment has potential to reduce acquisition of healthcare-associated infection(s).
S. Ali, A.P.R. Wilson
doaj   +2 more sources

In vitro response of THP-1 derived macrophages to antimicrobially effective PHMB-coated Ti6Al4V alloy implant material with and without contamination with S. epidermidis and P. aeruginosa [PDF]

Biomaterials Research, 2022
Aim Periprosthetic joint infections are a devastating complication after arthroplasty, leading to rejection of the prosthesis. The prevention of septic loosening may be possible by an antimicrobial coating of the implant surface.
Paula Zwicker, Thomas Schmidt, Melanie Hornschuh, Holger Lode, Axel Kramer, Gerald Müller   +5 more
doaj   +2 more sources

Organic Polyurethane Surface Structures to Manufacture Noneluting Antimicrobial Polyurethanes: A Systematic Review of Literature. [PDF]

Biomed Res Int
The dramatic increase in hospital‐acquired infections and healthcare costs associated with infection treatment and antimicrobial resistance in implant infections necessitates further research and development of antimicrobial implant material properties. Polyurethanes are key biomaterials used in medical implants and devices.
Hurck BJ, Vargas Guerrero MG, de Boer C, Dias AA, Arts JJC.   +4 more
europepmc   +2 more sources

Supercationic Poly(Hexamethylene Biguanide)‐Derived Carbon Dots for Combating Multidrug‐Resistant Bacterial Keratitis

Small Structures
Bacterial keratitis induced by multidrug‐resistant (MDR) bacteria is a formidable challenge, posing a significant threat to public vision. The compromised therapeutic efficiency against MDR bacteria and the risk of bacterial evolution due to excessive ...
Wenjie Fan, Tianji Feng, Hongxian Pan, Yin Zhang, Zhebin Chen, Qiao Jin, Haijie Han, Jian Ji, Ke Yao   +8 more
doaj   +2 more sources

Comparison of the in vitro antibiofilm activities of otic cleansers against canine otitis externa pathogens. [PDF]

Vet Dermatol
Background – Biofilm production by canine otitis externa (COE) pathogens and resistance development to multiple antimicrobials are commonly reported problems in veterinary practice. The use of adjuvants to disrupt biofilms may be a viable adjunctive therapy.
Savaliya BF, Kim S, Veltman T, Trott DJ.
europepmc   +2 more sources

Fabrication of Novel Antimicrobial Bio-Fibers Using Silk Wastage, Study of Poly (hexamethylene) Biguanide, and Silver Nanoparticles Interaction

Journal of Natural Fibers, 2017
Regenerated silk fibers were fabricated through dry-wet spinning process using N-methyl morpholine N-oxide and methanol as solvent and coagulant, respectively. Several concentrations of poly (hexamethylene) biguanide (PHMB) (0.27, 0.41, and 0.55 mL per 1 
Seyedeh Ameneh Siadat, Javad Mokhtari
doaj   +2 more sources