Antiseptic Chitosan-Poly(hexamethylene) Biguanide Hydrogel for the Treatment of Infectious Wounds [PDF]
Journal of Functional Biomaterials, 2023 Topical wound infections create the ideal conditions for microbial colonization and growth in terms of moisture, temperature, and nutrients. When they are not protected, numerous types of bacteria from the internal microbiota and the external environment
Irine Rose Antony +5 more
doaj +6 more sources
Study of Epigenetic Properties of Poly(HexaMethylene Biguanide) Hydrochloride (PHMB) [PDF]
International Journal of Environmental Research and Public Health, 2014 Poly(HexaMethylene Biguanide) hydrochloride (PHMB) CAS No. [32289-58-0] is a particularly effective member of the biguanides antiseptic chemical group, and has been in use since the early fifties in numerous applications. It has been proposed that PHMB be classified as a category 3 carcinogen although PHMB is not genotoxic.
Edmond E Creppy +2 more
exaly +8 more sources
Porous Poly(Hexamethylene Biguanide) Hydrochloride Loaded Silk Fibroin Sponges with Antibacterial Function [PDF]
Materials, 2020 In order to endue silk fibroin (SF) sponges with antibacterial function, positively charged poly(hexamethylene biguanide) hydrochloride (PHMB) was incorporated in SF through electrostatic interaction and by freeze-drying technique. The influence of PHMB on the structure and antibacterial activities of SF sponges was investigated.
Mingzhong Li, Li Mingzhong
exaly +5 more sources
3D-Printed PLDLA–TMC/PEG 400 Vascular Scaffolds with a Poly(hexamethylene Biguanide) Antibacterial Coating [PDF]
PharmaceuticsBackground: Synthetic vascular scaffolds often exhibit limited mechanical performance and low hydrophilicity, which compromise early vascular integration and increase susceptibility to bacterial colonization.
Monique M. Munhoz +8 more
doaj +4 more sources
Antiviral and Antibacterial 3D-Printed Products Functionalised with Poly(hexamethylene biguanide) [PDF]
PolymersInfection prevention and public health are a vital concern worldwide, especially during pandemics such as COVID-19 and seasonal influenza. Frequent manual disinfection and use of chemical spray coatings at public facilities are the typical measures taken to protect people from coronaviruses and other pathogens.
Anson M Y Luk +2 more
exaly +5 more sources
Journal of Natural Fibers, 2017 Regenerated silk fibers were fabricated through dry-wet spinning process using N-methyl morpholine N-oxide and methanol as solvent and coagulant, respectively. Several concentrations of poly (hexamethylene) biguanide (PHMB) (0.27, 0.41, and 0.55 mL per 1
Seyedeh Ameneh Siadat, Javad Mokhtari
doaj +3 more sources
Study on the Development of Antiviral Spandex Fabric Coated with Poly(hexamethylene biguanide) Hydrochloride (PHMB). [PDF]
Polymers (Basel), 2021 The spread of COVID-19 has brought about huge losses around the world. This study aims to investigate the applicability of PHMB used for developing antiviral spandex clothing against coronavirus. PHMB was qualitatively determined on the surface of spandex fabrics by using BPB.
Wang W, Yim SL, Wong CH, Kan CW.
europepmc +5 more sources
Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings [PDF]
Membranes, 2023 Wound infection is a common complication of chronic wounds. It can impair healing, which may not occur without external help. Antimicrobial dressings (AMDs) are a type of external help to infected chronic wounds.
Luís M. Vaz +3 more
doaj +2 more sources
Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review [PDF]
Membranes, 2022 The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
doaj +2 more sources
Effect of poly-hexamethylene biguanide hydrochloride (PHMB) treated non-sterile medical gloves upon the transmission of Streptococcus pyogenes, carbapenem-resistant E. coli, MRSA and Klebsiella pneumoniae from contact surfaces [PDF]
BMC Infectious Diseases, 2017 Background Reduction of accidental contamination of the near-patient environment has potential to reduce acquisition of healthcare-associated infection(s).
S. Ali, A.P.R. Wilson
doaj +2 more sources