Regenerated silk fibers were fabricated through dry-wet spinning process using N-methyl morpholine N-oxide and methanol as solvent and coagulant, respectively. Several concentrations of poly (hexamethylene) biguanide (PHMB) (0.27, 0.41, and 0.55 mL per 1
Seyedeh Ameneh Siadat, Javad Mokhtari
doaj +4 more sources
Study on the Development of Antiviral Spandex Fabric Coated with Poly(hexamethylene biguanide) Hydrochloride (PHMB). [PDF]
The spread of COVID-19 has brought about huge losses around the world. This study aims to investigate the applicability of PHMB used for developing antiviral spandex clothing against coronavirus. PHMB was qualitatively determined on the surface of spandex fabrics by using BPB.
Wang W, Yim SL, Wong CH, Kan CW.
europepmc +7 more sources
A biocompatible polylactide-ε-caprolactone polymer coated with poly(hexamethylene biguanide) displays antibacterial properties against slime-producing S. epidermidis [PDF]
Introduction: produced by renewable resources, biodegradable polymers with their competitive mechanical properties, thermal stability and biocompatibility are important alternatives to other synthetic materials for use in medical devices, i.e ...
Becker-Willinger, Carsten +7 more
core +4 more sources
Improved Adsorption of the Antimicrobial Agent Poly (Hexamethylene) Biguanide on Ti-Al-V Alloys by NaOH Treatment and Impact of Mass Coverage and Contamination on Cytocompatibility [PDF]
Unlike the native surface of the implant material (Ti6Al4V), oxidation with H2O2 leads to increased binding of the effective antimicrobial agent poly(hexamethylene) biguanide [PHMB]. However, treating with NaOH instead results in an even higher PHMB mass coverage.
Paula Zwicker +2 more
exaly +4 more sources
Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings [PDF]
Wound infection is a common complication of chronic wounds. It can impair healing, which may not occur without external help. Antimicrobial dressings (AMDs) are a type of external help to infected chronic wounds.
Luís M. Vaz +3 more
doaj +2 more sources
The disinfectant activity of poly(hexamethylene biguanide) (PHMB) has been explored in industrial applications, in agriculture and in food manipulation, but this biocide action is not completely understood. It is believed to arise from electrostatic interactions between the polyhexanide group and phosphatidylglycerol, which is the main phospholipid on ...
Gustavo Figueira de Paula +2 more
exaly +4 more sources
Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review [PDF]
The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
doaj +2 more sources
In vitro response of THP-1 derived macrophages to antimicrobially effective PHMB-coated Ti6Al4V alloy implant material with and without contamination with S. epidermidis and P. aeruginosa [PDF]
Aim Periprosthetic joint infections are a devastating complication after arthroplasty, leading to rejection of the prosthesis. The prevention of septic loosening may be possible by an antimicrobial coating of the implant surface.
Paula Zwicker +5 more
doaj +2 more sources
Comparison of the in vitro antibiofilm activities of otic cleansers against canine otitis externa pathogens [PDF]
Background – Biofilm production by canine otitis externa (COE) pathogens and resistance development to multiple antimicrobials are commonly reported problems in veterinary practice. The use of adjuvants to disrupt biofilms may be a viable adjunctive therapy.
Bhumika F. Savaliya +3 more
wiley +2 more sources
Conclusion of the opinion: On the basis of the data available, the SCCS concludes that Polyaminopropyl Biguanide (PHMB) is not safe for consumers when used as a preservative in cosmetic spray formulations and in all cosmetic products up to the maximum concentration of 0.3%.
Ulrike Bernauer
exaly +5 more sources

