Results 1 to 10 of about 20,567 (248)
Ultrasound-Responsive Dual-Prodrug Nanoassembly for "Fenestrae-Restoration Strategy" in Liver Fibrosis Therapy. [PDF]
Adv MaterLiu S +8 more
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Some of the next articles are maybe not open access.
Diabetes Care, 1992
The main biguanides, metformin and phenformin, were introduced in 1957 as oral glucose-lowering agents to treat non-insulin-dependent diabetes mellitus (NIDDM). Phenformin was withdrawn in many countries because of an association with lactic acidosis, but metformin does not have the same risk if appropriately prescribed. Metformin is now widely used as
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The main biguanides, metformin and phenformin, were introduced in 1957 as oral glucose-lowering agents to treat non-insulin-dependent diabetes mellitus (NIDDM). Phenformin was withdrawn in many countries because of an association with lactic acidosis, but metformin does not have the same risk if appropriately prescribed. Metformin is now widely used as
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Antidiabetic Behavior of Biguanides
Journal of Pharmaceutical Sciences, 1983The existence of active electron pairs on some nitrogen atoms in phenformin hydrochloride is inferred from the presence of a hydrogen catalytic polarographic wave. This finding emphasizes the ability of biguanides to form hydrogen bridges with other molecular species such as amino acids and proteins, as well as to form coordination complexes with zinc ...
F, Vicente-Pedrós +2 more
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Biguanides1 in some form have been used since medieval times. French lilac, or goat’s rue (galega officinalis), was used as a folk treatment for diabetes in southern and eastern Europe. Later, galega officinalis was found to be rich in the compound guanidine. In 1918, the hypoglycemic activity of guanidine was confirmed.
Mina Rena Chapler, Sidhartha D. Ray
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Mina Rena Chapler, Sidhartha D. Ray
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Spectrophotometric (UV) investigation on biguanide and substituted biguanides
Tetrahedron, 1972Abstract Biguanide base and its monosalts have absorption maxima at 230 mμ which has been attributed to π-π* transition. The spectral effect on replacement of a carbon π centre by a heteroatom nitrogen centre is discussed and attempt has been made to predict the spectral shifts in biguanide base and normal salts due to the substitution heteronitrogen
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Nihon rinsho. Japanese journal of clinical medicine, 2007
Caroline Day, Clifford J. Bailey
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Caroline Day, Clifford J. Bailey
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