Results 31 to 40 of about 20,567 (248)
Biguanides enhance antifungal activity against Candida glabrata
Virulence, 2018 Candida spp. are the fourth leading cause of nosocomial blood stream infections in North America. Candida glabrata is the second most frequently isolated species, and rapid development of antifungal resistance has made treatment a challenge.
Shuying Xu +13 more
doaj +1 more source
Acta Pharmaceutica, 2018 Extensive in vitro studies have been conducted to evaluate the anticancer activity of oral hypoglycemic agents. Many of these studies experienced detrimental limitations, since they were conducted on cancer cells commonly grown in culture media ...
Bardaweel Sanaa K. +3 more
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Safety assessment of Polyhexamethylene biguanide [PDF]
International Journal of Medical Device and Adjuvant Treatments, 2019 OBJECTIVE: The use of antiseptics in the treatment of genital infections has become a systematic alternative to antibiotics. Their use has been also supported for the treatment of virus-induced genital infections.
B. Orrù +3 more
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Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review
Membranes, 2022 The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
doaj +1 more source
Molecules, 2021 Bacterial strains become resistant to almost all classes of antibiotics, which makes it necessary to look for new substitutes. The non-absorbable ciprofloxacin–biguanide bismuth complex, used locally, may be a good alternative to a conventional therapy ...
Dorota Kowalczuk +5 more
doaj +1 more source
Antitumor Effects and Mechanisms of Metabolic Syndrome Medications on Hepatocellular Carcinoma
Journal of Hepatocellular Carcinoma, 2022 Kyoko Oura, Asahiro Morishita, Joji Tani, Tsutomu Masaki Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, JapanCorrespondence: Kyoko Oura, Department of Gastroenterology and Neurology, Kagawa University, 1750 ...
Oura K, Morishita A, Tani J, Masaki T
doaj
Frontiers in Pharmacology, 2018 The antidiabetic biguanide metformin exerts antiproliferative effects in different solid tumors. However, during preclinical studies, metformin concentrations required to induce cell growth arrest were invariably within the mM range, thus difficult to ...
Federica Barbieri +13 more
doaj +1 more source
Designed Lewis Acid–Base Passivation for High Performance Perovskite Solar Cells
Advanced Functional Materials, EarlyView.ABSTRACT Silicon's high cost and long energy payback time remain major barriers to the global expansion of solar power. In contrast, metal–halide perovskites offer abundant, solution‐processable absorbers, and have achieved efficiencies of 25%–30%, positioning them as strong competitors to silicon.
Afna Manaf +4 more
wiley +1 more source
Epidermal Patch Technologies for Integrated Healthcare and Infection Management
Advanced Healthcare Materials, EarlyView.Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang +7 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis +9 more
wiley +1 more source