Results 31 to 40 of about 18,459 (198)

Prophylaxis of Ocular Infection in the Setting of Intraocular Surgery: Implications for Clinical Practice and Risk Management

Ophthalmology and Therapy, 2023
In this review we discuss the role of intraocular surgery preoperative prophylaxis. The correct choice of antimicrobial drug is variable in each surgical setting, according to the available strengths of evidence, the anatomical district involved, and the
Alfredo Borgia, Daniela Mazzuca, Marcello Della Corte, Nicola Gratteri, Giovanni Fossati, Raffaele Raimondi, Luca Pagano, Vincenzo Scorcia, Giuseppe Giannaccare   +8 more
doaj   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

Positional Isomer Engineering for Crystallization Kinetics Control in Wide‐Bandgap Perovskite Solar Cells

Carbon Energy, EarlyView.
Based on the ortho‐para configuration of the amino‐sulfonic acid group, 2,4‐diaminobenzenesulfonic acid (2,4‐DABSA) forms the strongest coordination with the perovskite precursor among its isomers, guiding a unique “fast nucleation followed by slow crystallization” kinetics.
Jun Chu, Chaoqi Liu, Xi Yang, Xiuhua Chen, Tao Zhu, Shaoyuan Li, Zhongqiu Tong, Huidong Ma, Jianjun Zhang, Jianghui Zheng, Wenhui Ma, Jessica Yajie Jiang   +11 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Poly(hexamethylene biguanide) salicylate as a novel ionic liquid with antibacterial properties in the production of poly(vinyl alcohol) films

Materials Research Express, 2022
The presented work describes the effect of poly(hexamethylene biguanide) salicylate (PHMB-SA) ionic liquid on the properties of poly(vinyl alcohol) film. The ionic liquid synthetized is used as an antimicrobial agent. The ionic liquid consist of the poly(
Anna Słubik, Iwona Masłowska-Lipowicz, Dorota Wieczorek, Łucja Wyrębska   +3 more
doaj   +1 more source

Correlations Among Glycemia and Glucose Variability, Thyroid Hormones, and Albuminuria in Patients With Type 2 Diabetes Mellitus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hyperglycemia, glucose fluctuations, and thyroid dysfunction contribute to the progression of diabetic nephropathy. This study aimed to investigate the associations of glycemia, glucose variability, and thyroid hormones with albuminuria in patients with type 2 diabetes mellitus (T2DM). In total, 451 T2DM patients were included.
Na Luo, Shang‐Yong Feng, Hui Chen, Dun‐Min She, Yan Liu, Ying Li, Cai‐Feng Yan, Zhen‐Wen Zhang, Jing Chen, Xiao‐Li Cai, Gao‐Yu Zhao, Hui Yu, Yan Wang   +12 more
wiley   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2013
Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene
Genevieve Walls, Lisa Noonan, Elizabeth Wilson, David Holland, Simon Briggs   +4 more
doaj   +1 more source

Chlorhexidine 0.02% or polyhexamethylene biguanide 0.02% as the main treatment for Acanthamoeba keratitis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report medical cure and treatment failure rates of Acanthamoeba keratitis (AK) with respect to type of treatment, disease stage and prognostic factors. Methods Electronic records were reviewed for 45 patients with PCR‐positive AK treated at the Department of Ophthalmology, Aarhus University Hospital, Denmark from 2012 to 2025 ...
Anders Ivarsen, Sandra M. Skovdal, Stine Elkjær Nielsen, Christen Rune Stensvold, Henrik Vedel Nielsen, Jesper Hjortdal   +5 more
wiley   +1 more source

The Activity of PHMB and Other Guanidino Containing Compounds against Acanthamoeba and Other Ocular Pathogens

Microorganisms, 2022
In recent years, a rise in the number of contact lens users in the UK and worldwide coincided with an increased incidence of microbial keratitis. The aim of this study was to investigate the antimicrobial activities of polyhexamethylene guanidine (PHMG),
Dharanga Ratnayake, Michael Ansah, Enas Al Ani, Wayne Heaselgrave   +3 more
doaj   +1 more source