Results 51 to 60 of about 20,567 (248)

Effect of Local Administration of Meglumine Antimoniate and Polyhexamethylene Biguanide Alone or in Combination with a Toll-like Receptor 4 Agonist for the Treatment of Papular Dermatitis due to Leishmania infantum in Dogs [PDF]

open access: gold, 2023
Icíar Martínez-Flórez   +10 more
openalex   +1 more source

Effects of Biguanide-PROTACs in Pancreatic Cancer Cells

open access: yesMolecules
This study focuses on the synthesis of Biguanide-PROTACs, formed by conjugating the biguanide motif with a spacer and a ligand for recognition subunits of two E3 ubiquitin ligases.
Julie Vatté   +3 more
doaj   +1 more source

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano   +4 more
wiley   +1 more source

Single‐ or two‐visits endodontic treatment: Impact of irrigants on surface roughness, microhardness, topography, and fracture resistance of root dentin

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract This study evaluated the effect of the number of simulated endodontic treatment visits and the type of irrigant on the surface roughness, microhardness, topography, and fracture resistance of root dentin. Bovine roots were distributed into six groups (n = 14) according to the irrigant and number of treatment visits: 0.9% saline solution ...
Yasmin Padoin   +5 more
wiley   +1 more source

ANTIBACTERIAL ACTIVITY AND QUANTIFICATION OF POLYHEXAMETHTYLENE BIGUANIDE HYDROCHLORIDE IN MUSCULAR TISSUES AND VISCERA OF BROILERS ATIVIDADE ANTIBACTERIANA E QUANTIFICAÇÃO DE CLORIDRATO DE POLIHEXAMETILENO BIGUANIDA (P.H.M.B.) EM TECIDOS MUSCULARES E VÍCERAS DE FRANGOS

open access: yesPesquisa Agropecuária Tropical, 2007
<!-- @page { margin: 2cm } --> <p class="western" align="justify">Trials were carried out in order to check the viability of polyhexamethylene biguanide hydrochloride in the control of pathogenic and degenerating bacteria in carcass of ...
Albenones José de Mesquita   +3 more
doaj   +1 more source

Disposable negative pressure wound therapy system enhances punch graft acceptance in equine distal limb wounds

open access: yesEquine Veterinary Education, EarlyView.
Summary This case series describes the use of a disposable, canister‐free negative pressure wound therapy (NPWT) system (PICO®) in combination with punch grafting for the treatment of distal limb wounds in three horses. Each horse presented with complex traumatic injuries resulting in delayed or inadequate healing of distal limb wounds.
M. Schnierer   +2 more
wiley   +1 more source

Diagnosis and management of equine metabolic syndrome

open access: yesEquine Veterinary Education, EarlyView.
Summary Equine metabolic syndrome (EMS) is a prevalent endocrine disorder that increases the risk of hyperinsulinaemia‐associated laminitis (HAL), the most common and clinically significant form of laminitis. The central pathological feature of EMS is insulin dysregulation (ID), which encompasses basal or postprandial hyperinsulinaemia and tissue ...
F. R. Bertin
wiley   +1 more source

Determination of polyhexamethylene biguanide hydrochloride

open access: yesReviews in Analytical Chemistry, 2014
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used as a disinfectant in personal care products such as cosmetics and toiletries and as a sanitizer in swimming pools. PHMB-HCl possesses marked characteristics of cationic polyelectrolytes.
Masadome Takashi, Hattori Toshiaki
doaj   +1 more source

Double-Biguanide Therapy for Resistant Acanthamoeba Keratitis

open access: yesCase Reports in Ophthalmology, 2011
Aims: To report the clinical and diagnostic findings of a patient with Acanthamoeba keratitis resistant to both polyhexamethylene biguanide (PHMB)-hexamidine and chlorhexidine-hexamidine treatment.
Giulio Ferrari   +2 more
doaj   +1 more source

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