Results 71 to 80 of about 18,459 (198)

Evaluation of sanitizers efficiency over spore forming bacteria isolated from whole UHT milk

Revista do Instituto de Latícinios Cândido Tostes, 2017
It is known that sporulated bacteria produce proteolytic and lipolytic thermoresistant enzymes associated with technological problems such as off-flavors, age gelation and bitter taste in milk and dairy products.
Edite Andrade Costa, Leonardo Justino Carioca, Valdeir Viana Freitas, Maurilio Lopes Martins, Aurélia Dornelas de Oliveira Martins, Cláudia Lúcia de Oliveira Pinto   +5 more
doaj   +1 more source

Effects of Oral Semaglutide on Dietary Intake and Body Composition in Japanese People With Type 2 Diabetes: A Prospective Observational Study in Clinical Practice

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
This prospective observational study evaluated changes in dietary patterns and body composition after 3 months of oral semaglutide treatment in people with Type 2 diabetes. Oral semaglutide was associated with reduced energy intake, salt intake and body fat while preserving handgrip strength.
Mika Sawada, Naoko Nakanishi, Masakazu Aihara, Kanako Ohkuma, Shoko Hamano, Yoshitaka Sakurai, Rie Sekine, Satoshi Usami, Toshimasa Yamauchi, Naoto Kubota   +9 more
wiley   +1 more source

Sexual Safety Signals of Common Antidiabetic Drugs: Insights From FAERS Disproportionality Analysis

Andrology, Volume 14, Issue 6, Page 1627-1635, September 2026.
ABSTRACT Background Erectile dysfunction is a prevalent and distressing complication of diabetes mellitus that markedly affects quality of life in male patients. Although the role of diabetes in erectile dysfunction is well‐established, potential drug‐induced sexual dysfunction associated with commonly prescribed antidiabetic medications remains ...
Shan Lin, Xuefeng Ding, Xin Dang, Qingyuan Zhan   +3 more
wiley   +1 more source

Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway

Cell Reports Medicine
Summary: The biguanide metformin attenuates mitochondrial oxidation and is proposed as an anti-cancer therapy. However, recent clinical studies suggest increased proliferation and fatty acid β-oxidation (FAO) in a subgroup of patients with breast cancer (
Jun Hyoung Park, Kwang Hwa Jung, Dongya Jia, Sukjin Yang, Kuldeep S. Attri, Songyeon Ahn, Divya Murthy, Tagari Samanta, Debasmita Dutta, Meron Ghidey, Somik Chatterjee, Seung Yeop Han, Diego A. Pedroza, Abha Tiwari, Joyce V. Lee, Caitlin Davis, Shuting Li, Vasanta Putluri, Chad J. Creighton, Nagireddy Putluri, Lacey E. Dobrolecki, Michael T. Lewis, Jeffrey M. Rosen, José N. Onuchic, Andrei Goga, Benny Abraham Kaipparettu   +25 more
doaj   +1 more source

Metformin: Focus on Melanoma

Frontiers in Endocrinology, 2018
Metformin is the most common biguanide used in the treatment of diabetes, with 120 million treated patients worldwide. Metformin decreases hyperglycemia without inducing hypoglycemia in diabetic patients and is very well tolerated.
Emilie Jaune, Emilie Jaune, Stéphane Rocchi, Stéphane Rocchi   +3 more
doaj   +1 more source

Ueber Biguanid [PDF]

Berichte der deutschen chemischen Gesellschaft, 1879
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openaire   +2 more sources

Comparing the effects of biguanides and dipeptidyl peptidase-4 inhibitors on cardio-cerebrovascular outcomes, nephropathy, retinopathy, neuropathy, and treatment costs in diabetic patients.

PLoS ONE
BackgroundWestern guidelines often recommend biguanides as the first-line treatment for diabetes. However, dipeptidyl peptidase-4 (DPP-4) inhibitors, alongside biguanides, are increasingly used as the first-line therapy for type 2 diabetes (T2DM) in ...
Eiji Nakatani, Hiromitsu Ohno, Tatsunori Satoh, Daito Funaki, Chikara Ueki, Taku Matsunaga, Takayoshi Nagahama, Toru Tonoike, Hiromichi Yui, Akinori Miyakoshi, Yoshihiro Tanaka, Ataru Igarashi, Hiraku Kumamaru, Nagato Kuriyama, Akira Sugawara   +14 more
doaj   +1 more source

Diagnosis and management of equine metabolic syndrome

Equine Veterinary Education, Volume 38, Issue 9, Page 471-480, September 2026.
Summary Equine metabolic syndrome (EMS) is a prevalent endocrine disorder that increases the risk of hyperinsulinaemia‐associated laminitis (HAL), the most common and clinically significant form of laminitis. The central pathological feature of EMS is insulin dysregulation (ID), which encompasses basal or postprandial hyperinsulinaemia and tissue ...
F. R. Bertin
wiley   +1 more source

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis.

PLoS Biology, 2015
Metformin is a biguanide widely prescribed to treat Type II diabetes that has gained interest as an antineoplastic agent. Recent work suggests that metformin directly antagonizes cancer cell growth through its actions on complex I of the mitochondrial ...
Takla Griss, Emma E Vincent, Robert Egnatchik, Jocelyn Chen, Eric H Ma, Brandon Faubert, Benoit Viollet, Ralph J DeBerardinis, Russell G Jones   +8 more
doaj   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source