Results 81 to 90 of about 18,459 (198)

Comparative Evaluation of the Antihyperglycemic Potential of Coccinia cordifolia and Gynura procumbens Leaf Extracts: Integrated Phytochemical, In Vivo, Molecular Docking, and DFT Investigations

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Graphical abstract illustrating the overall experimental workflow and antidiabetic evaluation of Coccinia cordifolia and Gynura procumbens extracts. Plant materials were extracted and subsequently investigated through in vivo antidiabetic studies, density functional theory (DFT) analysis, and in silico molecular docking to identify potential bioactive ...
A. J. M. Morshed, Sujan Kanti Das, Zobayed Islam, Mamuna Akter, Muhammad Abu Bakar, Mohammad Mostafa, Rasheda Akter, Tania Sharmin, Mohammad Helal Uddin   +8 more
wiley   +1 more source

Waist‐to‐Body Mass Index Ratio and Risk of Musculoskeletal Disease in Type 2 Diabetes: A Cohort and PhIP‐Seq Analysis

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Musculoskeletal complications in type 2 diabetes (T2DM) are inadequately captured by body mass index (BMI). Waist‐to‐BMI ratio (WBR) may better reflect adverse body composition. We examined cross‐sectional and longitudinal associations between WBR and musculoskeletal disorders in T2DM.
Yongze Zhang, Luxi Lin, Lifeng Zheng, Xiaohuang Lin, Zhaowei Xu, Ximei Shen, Lingning Huang, Fengying Zhao, Sunjie Yan   +8 more
wiley   +1 more source

Seasonal Restructuring of Microbial Communities and Resistomes in the Shitalakshya River, Bangladesh Revealed by Shotgun Metagenomics

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Dry‐season pollutant concentration drives microbial restructuring in Bangladesh's Shitalakshya River, shifting communities from Myroides to stress‐tolerant genera while enriching metal resistance genes and efflux pumps, revealing non‐antibiotic co‐selection as a key driver of antimicrobial resistance in urban waters.
Muhammad Ehteshamul Haque, Md. Shaminur Rahman, Munawar Sultana, Anowara Begum   +3 more
wiley   +1 more source

Comparative Analysis of Chlorhexidine Derivatives and Alternative Agents on Streptococcus mutans Viability, Biofilm Formation, and Gene Expression

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Chlorhexidine gluconate and alexidine potently kill S. mutans, disrupt biofilms, and downregulate virulence genes, yet show moderate cytotoxicity. In contrast, sub‐MIC amoxicillin paradoxically promotes biofilm formation, highlighting the need for targeted antibiofilm therapies. ABSTRACT This study evaluates the antimicrobial and antibiofilm effects of
Hamideh Kamalloo, Mohammadreza Moeininejad, Maryam kiani golshoui, Fatemeh Samadyar, Ali Shivaee, Behrooz Sadeghi Kalani   +5 more
wiley   +1 more source

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source

Biguanide chitosan microneedles with cell-free DNA scavenging ability for psoriasis therapy

Bioactive Materials
High levels of cell-free DNA (cfDNA) induce psoriasis. Currently, the treatment of psoriasis has the disadvantages of penetration difficulty, suppression of normal immunity, and skin irritation.
Zihao Liu, Yu Wang, Yuhan Zhang, Liufu Hu, Bozhi Chen, Yang Li, Xindong Guo, Bingran Yu, Fu-Jian Xu   +8 more
doaj   +1 more source

Mapping Obesity Care Pathways and Healthcare Resource Use From 2015 to 2019 in England

Obesity Science &Practice, Volume 12, Issue 4, August 2026.
ABSTRACT Objective This observational study characterized obesity care pathways and healthcare resource use in England between 2015 and 2019. Methods Data were obtained from Discover and the Salford Integrated Record (SIR), two databases of linked primary and secondary electronic health records in England. Adults with a body mass index (BMI) ≥ 30 kg/m2
Alexander Dimitri Miras, Silvia Capucci, Sylwia Migas, Bozydar Wrona, Liwei Zhao, Johann Castañeda‐Sanabria, Lise M. Hagelund, Vasileios Antavalis, Camilla S. Morgen   +8 more
wiley   +1 more source

Development and validation of a nomogram for predicting the risk of poor prognosis in patients with cerebral infarction

Heliyon
Objective: To identify factors related to poor prognosis in patients with cerebral infarction (CI) and to construct and validate a personalized prediction model based on these factors.
Zhenfeng Chen, Lixiang Zhang, Rui Li, Haiying Hu, Qiongdan Hu, Xia Chen   +5 more
doaj   +1 more source

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6509-6532, August 2026.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano, Line L. Haurum, Christine R. Schwarz, Francesca Porcellati, Andreas Andersen   +4 more
wiley   +1 more source

Real‐World Effectiveness and Safety of iGlarLixi in People With Type 2 Diabetes in LATAM Region: A Subanalysis of the SUCCESS Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8724-8728, September 2026.
Juan Manuel Arteaga‐Diaz, Jose Luis Torres‐Grajales, Leobardo Sauque‐Reyna, Carlos Salamanca‐Carrillo, Luis Anguiano‐Medrano   +4 more
wiley   +1 more source