Background: The significance of central line-associated bloodstream infection (CLABSI) is that it increases morbidity, mortality, and treatment costs. The incidence of infections is reduced by the use of antibiotic-impregnated dressings at the central catheter insertion site. In this context, polyhexamethylene biguanide (PHMB)-containing dressings have
Mohadeseh Zamanian +3 more
openalex +2 more sources
Incorporation of biguanide compounds into poly(GL)-b-poly(GL-co-TMC-co-CL)-b-poly(GL) monofilament surgical sutures [PDF]
A new biodegradable coating was developed for bioabsorbable monofilament sutures. Specifically, a random copolymer having 35 wt-% and 65 wt-% of lactide and trimethylene carbonate units showed appropriate flexibility, stickiness and degradation rate, as ...
Cabral, Tània +6 more
core +2 more sources
Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]
Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core +1 more source
The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile +41 more
core +3 more sources
Biguanide-, imine-, and guanidine-based networks as catalysts for transesterification of vegetable oil [PDF]
Polycationic systems based on poly(hexamethylene biguanide) (PHMBG), branched polyethyleneimine (PEI) and poly(N-vinylguanidine) (PVG) have been evaluated as heterogeneous catalysts for the transesterification of sunflower oil by methanol.
Alvarez, Michael +4 more
core +1 more source
3D Bioprinting of Lignocellulosic Biomaterials
Lignocellulosic biomaterials are nanostructured polymer materials that possess unique properties, making them promising for use in 3D bioprinting. This article reviews recent progress in the application of different lignocellulosic materials (cellulose, hemicellulose, and lignin) from various sources in the field of 3D bioprinting.
Amin Shavandi +5 more
wiley +1 more source
New poly(ester urea) derived from L-leucine: Electrospun scaffolds loaded with antibacterial drugs and enzymes [PDF]
Electrospun scaffolds from an amino acid containing poly(ester urea) (PEU) were developed as promising materials in the biomedical field and specifically in tissue engineering applications. The selected poly(ester urea) was obtained with a high yield and
Díaz Andrade, Angélica María +4 more
core +2 more sources
Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus [PDF]
The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is limited.
Chivu, A +3 more
core +3 more sources
Surgical sutures are widely utilized medical devices for the purpose of closing wounds after surgical interventions. During surgical procedures, sutures can come into contact with microorganisms in the surrounding environment, leading to the development of bacterial biofilms and subsequent surgical site infections (SSI).
Ogün Bozkaya +3 more
openalex +3 more sources
Evaluation of The Interaction Between Alternative Endodontic Irrigation Solutions [PDF]
Statement of the problem: For successful endodontic treatment, mecha-nical cleaning and chemical irrigation can be used together. Since there is not yet a single solution sufficient for both root canal cleaning alone, combined use of irrigants is ...
Erdoğan, Hilal, Kaplan, Melek Hilal
core +1 more source

