Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review [PDF]
Membranes, 2022 The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
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Materials Research Express, 2022 The presented work describes the effect of poly(hexamethylene biguanide) salicylate (PHMB-SA) ionic liquid on the properties of poly(vinyl alcohol) film. The ionic liquid synthetized is used as an antimicrobial agent. The ionic liquid consist of the poly(
Anna Słubik +3 more
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In vitro response of THP-1 derived macrophages to antimicrobially effective PHMB-coated Ti6Al4V alloy implant material with and without contamination with S. epidermidis and P. aeruginosa [PDF]
Biomaterials Research, 2022 Aim Periprosthetic joint infections are a devastating complication after arthroplasty, leading to rejection of the prosthesis. The prevention of septic loosening may be possible by an antimicrobial coating of the implant surface.
Paula Zwicker +5 more
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Computational and Theoretical Chemistry, 2022 In the current study, the toxic material Poly-hexamethylene biguanide hydrochloride (PHMB) has been characterized by UV–Visible and infrared spectroscopy in different solvent environments. The nature of the molecular interactions between solvent molecules and PHMB via hydrogen bonds has been investigated using the Atoms in Molecules (AIM) and non ...
Sibel Çelik
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Improved Adsorption of the Antimicrobial Agent Poly (Hexamethylene) Biguanide on Ti-Al-V Alloys by NaOH Treatment and Impact of Mass Coverage and Contamination on Cytocompatibility [PDF]
Coatings, 2021 Unlike the native surface of the implant material (Ti6Al4V), oxidation with H2O2 leads to increased binding of the effective antimicrobial agent poly(hexamethylene) biguanide [PHMB]. However, treating with NaOH instead results in an even higher PHMB mass coverage.
Paula Zwicker +2 more
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Poly (hexamethylene biguanide), adsorbed onto Ti-Al-V alloys, kills slime-producing Staphylococci and Pseudomonas aeruginosa without inhibiting SaOs-2 cell differentiation [PDF]
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2020 Antimicrobial coating of implant material with poly(hexamethylene biguanide) hydrochloride (PHMB) may be an eligible method for preventing implant-associated infections.
Finke, Birgit +5 more
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Small StructuresBacterial keratitis induced by multidrug‐resistant (MDR) bacteria is a formidable challenge, posing a significant threat to public vision. The compromised therapeutic efficiency against MDR bacteria and the risk of bacterial evolution due to excessive ...
Wenjie Fan +8 more
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Polyhexanide and chlorhexidine loaded chitosan wound dressings [PDF]
Ann Med, 2021 in proceedings of the Fourth International Congress of CiiEM: Health, Well-Being and Ageing in the 21st Century, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from 3–5 June 2019.This is an Open Access article distributed under the ...
Nydrioti E, Saramago B, Serro A.
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Formation, properties and stability of poly(hexamethylene biguanide) stabilised silver nanoparticles from the perspective of novel antimicrobial agents [PDF]
, 2021 Rising antimicrobial resistance has increased pressure to develop novel antimicrobial agents. Poly(hexamethylene biguanide) stabilised silver nanoparticles have been suggested as a potential candidate exhibiting strong biocidal properties.
Sacharczuk, Jakub
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A biocompatible polylactide-ε-caprolactone polymer coated with poly(hexamethylene biguanide) displays antibacterial properties against slime-producing S. epidermidis [PDF]
Materials AdvancesIntroduction: produced by renewable resources, biodegradable polymers with their competitive mechanical properties, thermal stability and biocompatibility are important alternatives to other synthetic materials for use in medical devices, i.e ...
Becker-Willinger, Carsten +7 more
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