BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Kinases and PhosphatasesMetal–organic frameworks (MOFs) have been increasingly recognized as promising platforms for enzyme modulation, owing to their tunable porosity, high surface area, and versatile chemical functionality.
Azizah Alamro, Thanih Balbaied
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SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Editorial: Kinase/phosphatase signaling and axonal function in health and disease
Frontiers in Cellular Neuroscience, 2023 Gerardo Morfini, Stefan Kins
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Soil biological quality in short- and long-term field trials with conventional and organic fertility input types [PDF]
, 2007 Soils of the DOK trial and three other field trials with manure input were analysed for effects on soil biology. While long-term effects indicate a new steady state at the DOK trial site, differences at the other field trials suggest that fresh manure at
Bruns, Christian +6 more
core
Dynamics of acid phosphatase production of the ectomycorrhizal mushroom Cantharellus tropicalis. [PDF]
, 2011 Rohit Sharma +2 more
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Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid
Advanced Functional Materials, EarlyView.In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang +16 more
wiley +1 more source
Sex‐Specific Associations of Serum Alkaline Phosphatase With Metabolic Syndrome and Its Components: Over 15 Years of Follow‐Up Among Iranian Adults [PDF]
Parto Hadaegh +5 more
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Figure 2 of 'Structural basis for the specificity of PPM1H phosphatase for Rab GTPases'
, 2021 Paweł Lis +2 more
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