Results 141 to 150 of about 1,127,331 (318)
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai+9 more
wiley +1 more source
BLOOD PHOSPHATASE AND THE VAN DEN BERGH REACTION IN THE DIFFERENTIATION OF THE SEVERAL TYPES OF JAUNDICE [PDF]
W. M. Roberts
openalex +1 more source
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen+5 more
wiley +1 more source
Phosphatase to kinase switch of a critical enzyme contributes to timing of cell differentiation
Cell differentiation is an essential biological process that is subject to strict temporal regulation. Caulobacter crescentus undergoes obligate differentiation from a swarmer cell to a stationary, replication-competent stalked cell with each cell cycle.
Trisha N. Chong+3 more
doaj +1 more source
Bistable MAP Kinase Activity: A Plausible Mechanism Contributing to Maintenance of Late Long-Term Potentiation [PDF]
Bistability of MAP kinase (MAPK) activity has been suggested to contribute to several cellular processes, including differentiation and long-term synaptic potentiation. A recent model (48) predicts bistability due to interactions of the kinases and phosphatases in the MAPK pathway, without feedback from MAPK to earlier reactions.
arxiv
Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo+10 more
wiley +1 more source
Quorum sensing contributes to activated B cell homeostasis and to prevent autoimmunity [PDF]
Maintenance of plasma IgM levels is critical for immune system function and homeostasis in humans and mice. However, the mechanisms that control homeostasis of the activated IgM-secreting B cells are unknown. After adoptive transfer into immune-deficient hosts, B-lymphocytes expand poorly but fully reconstitute the pool of natural IgM-secreting cells ...
arxiv
Supervariate Gel Transforms into Various Biominerals in Salt Solutions
It is revealed that common calcium‐based biominerals can form from a stable, non‐toxic ‘supervariate’ gel. This tunable gel selectively yields calcite or hydroxyapatite in carbonate/phosphate solutions, while CaCl₂ facilitates the formation of dihydrate calcium pyrophosphate, which converts to hydroxyapatite upon drying. These findings provide insights
Xinxue Tang+12 more
wiley +1 more source
Cerium Oxide Nanoparticles Role as Antioxidant
Cerium oxide nanoparticles (NPs), also known as ceria NPs, are particles of cerium oxide with sizes in the nanometer range. Cerium oxide (CeO2) is a compound composed of cerium and oxygen, and when it is reduced to NPs, it exhibits unique properties and ...
Sura A. Abdulsattar
doaj +1 more source