Results 51 to 60 of about 1,989,916 (296)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Modification and validation of cracked zone range under coupled in-situ stress and blasting load

Scientific Reports
Exploring the characteristics of blasting crack propagation under the action of in-situ stress is of great significance for guiding the layout of blast holes on site.
Xingchao TIAN, Tiejun TAO, Lang HUANG
doaj   +1 more source

Influence of Organic Impurities on Fractional Crystallization of NaCl and Na₂SO₄ from High-Salinity Coal Chemical Wastewater: Thermodynamics and Nucleation Kinetics Analysis

Molecules
It is a valid path to realize the zero discharge of coal chemical wastewater by using the fractional crystallization method to recycle the miscellaneous salt in high-salinity wastewater. In this study, the thermodynamics and nucleation kinetics of sodium
Bo Shen, Bo Zhao, Hai Du, Yongsheng Ren, Jianwei Tang, Yong Liu, Quanxian Hua, Baoming Wang   +7 more
doaj   +1 more source

Special issue in honour of Prof. Reto J. Strasser - Phosphorus deficiency affects the I-step of chlorophyll a fluorescence induction curve of radish

Photosynthetica, 2020
Phosphorus (P) is an essential nutrient for plant development and its fertilisation efficiency is an important issue in agriculture. Difficulties in diagnosing P deficiency in plants have created a demand for a quick and noninvasive method/tool for ...
M.D. CETNER, H.M. KALAJI, W. BORUCKI, K. KOWALCZYK   +3 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Study on the stability of iron tailings dam improved by curing agent

Frontiers in Earth Science
Fine-grained tailings exhibit poor permeability, prolonged consolidation time, low mechanical strength, and difficulty in dissipating excess pore water pressure.
Shujian Li, Guangjin Wang, Menglai Wang, Menglai Wang, Xidong Du, Bing Zhao, Jun You, Yuanting Zhu, Zhanglong Pu, Jiantao Pang, Rong Lan, Mingsheng Liu   +11 more
doaj   +1 more source

Continuous enzyme-coupled assay of phosphate- or pyrophosphate-releasing enzymes

BioTechniques, 2012
A coupled enzyme assay able to monitor the kinetics of reactions catalyzed by phosphate- or pyrophosphate-releasing enzymes is presented here.
Antonio S. Guillén Suárez, Alessandra Stefan, Silvia Lemma, Emanuele Conte, Alejandro Hochkoeppler   +4 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Application research on low cost support method for surrounding rock of broken section roadway in phosphate mine area

Frontiers in Earth Science
Introduction: Taking a phosphate mine in Yunnan as the engineering research background, the fractured rock mass of the No. 1 belt roadway is selected as the research object.Methods: To reduce the cost of tunnel surrounding rock support and optimize ...
Mengchao Xu, Xiaoshuang Li, Xiaoshuang Li, Jiawen Wang, Mengzhen Cao, Menglai Wang, Shujian Li   +6 more
doaj   +1 more source