Results 121 to 130 of about 87,366 (344)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Serum Phosphorus and Pill Burden Among Hemodialysis Patients Prescribed Sucroferric Oxyhydroxide: One-Year Follow-Up on a Contemporary Cohort

International Journal of Nephrology and Renovascular Disease, 2022
Jessica B Kendrick,1 Meijiao Zhou,2 Linda H Ficociello,2 Vidhya Parameswaran,2 Claudy Mullon,2 Michael S Anger,2,3 Daniel W Coyne4 1University of Colorado Anschutz Medical Campus, Aurora, CO, USA; 2Fresenius Medical Care Global Medical Office, Waltham ...
Kendrick JB, Zhou M, Ficociello LH, Parameswaran V, Mullon C, Anger MS, Coyne DW   +6 more
doaj  

THE EFFECT OF BINDER TYPE AND MAJOR DILUENT ON THE MIGRATION AND BIOAVAILABILITY OF RIBOFLAVIN SODIUM PHOSPHATE DURING TABLET MAKING [PDF]

, 2007
H M Elsabbagh, A. Nouh, Osama Soliman, Mariza Fouad Boughdady   +3 more
openalex   +1 more source

Production of phosphate binder fire-protective coating for steel building constructions [PDF]

, 2012
Brief analysis of means for fire protection of steel building constructions was given, special attention being paid to the advantages of using phosphate binders for protective coatings.
Kuzmenkov, M. I., Rumynskaya, E. I.
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Serum phosphate level at initiation of dialysis is associated with all-cause mortality: a multicenter prospective cohort study

Renal Failure, 2018
Introduction: As glomerular filtration rate (GFR) decreases, serum phosphate level increases. Previous reports indicated that serum phosphate level was associated with mortality in patients on dialysis.
Akiko Owaki, Daijo Inaguma, Isao Aoyama, Shinichiro Inaba, Shigehisa Koide, Eri Ito, Kazuo Takahashi, Hiroki Hayashi, Midori Hasegawa, Yukio Yuzawa, AICOPP group   +10 more
doaj   +1 more source

Intact FGF23 predicts serum phosphate improvement after combined nicotinamide and phosphate binder treatment in hemodialysis patients. [PDF]

Clin Kidney J, 2023
Egli-Spichtig D, Hamid AK, Arroyo EMP, Ketteler M, Wiecek A, Rosenkranz AR, Pasch A, Lorenz H, Hellmann B, Karus M, Ammer R, Rubio-Aliaga I, Wagner CA.   +12 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Safety and Phosphate‐Binding Capacity of Oxylanthanum Carbonate in Healthy Volunteers

Clinical and Translational Science
Despite the widespread use of currently available serum phosphate management options, elevated serum phosphate is common in patients with end‐stage kidney disease on dialysis.
Pablo E. Pergola, Melanie S. Joy, Armando Garsd, Steve J. Hasal, Atul Khare, Guru Reddy, Pramod Gupta, William F. Finn   +7 more
doaj   +1 more source

Effect of Tenapanor on Phosphate Binder Pill Burden in Hemodialysis Patients. [PDF]

Kidney Int Rep, 2021
Akizawa T, Sato Y, Ikejiri K, Kanda H, Fukagawa M.   +4 more
europepmc   +1 more source