Optimization of formulations of chloroquine phosphate tablets containing Ofada rice (Oryza glaberrina) starch as a binder: a Taguchi based grey-relational design [PDF]
Adenike Okunlola
openalex +1 more source
Direct and Binder-Free MXene-Assisted Cobalt Manganese Phosphate Electrode Fabrication on Carbon Cloth by Electrosynthesis for Efficient Supercapacitors [PDF]
Sajjad Hussain +8 more
openalex +1 more source
Studi Kemampuan Pati Biji Durian Sebagai Bahan Pengikat Dalam Tablet Ketoprofen Secara Granulasi Basah [PDF]
Many type of starch from various plants can be exploited as an alternative for additional materials in tablet formulation. One of the source that have been developed as a pharmaceutical excipient is durian seed starch, which relatively easy to find in
Firli, R. D. (Rosmala) +1 more
core
Halogen Bonding in Nucleic Acid Complexes
Halogen bonding (X-bonding) has attracted notable attention among noncovalent interactions. This highly directional attraction between a halogen atom and an electron donor has been exploited in knowledge-based drug design. A great deal of information has
Kolář, Michal H., Tabarrini, Oriana
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
In this activity, students focus on the physical and chemical processes associated with the Charleston Bump, a series of rocky scarps, mounds, overhangs, and flat pavements that rise from more than 700 m at the surface of the Blake Plateau to within 400 ...
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The effect of phosphate binder therapy with sucroferric oxyhydroxide on calcification propensity in chronic haemodialysis patients: a randomized, controlled, crossover trial. [PDF]
Thiem U +9 more
europepmc +1 more source

