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Internal Inconsistencies Between Reported Profiles, Predictors, and Conclusions. [PDF]
Ther Apher DialCankaya E.
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Serum calcium dynamics and risk of all-cause hospitalization and mortality in hemodialysis patients: a landmark analysis from the international DOPPS. [PDF]
Clin Kidney JIseri K, Yamazaki T, Taki I, Hida N.
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Next-Generation Phosphate Binders: Focus on Iron-Based Binders
Drugs, 2014Phosphate excess is associated with increased mortality in patients with chronic kidney disease (CKD) and has recently been linked to accelerated aging. Oral phosphate binders are prescribed to patients with CKD to prevent absorption of dietary phosphate. Currently available binders have been associated with impaired outcomes (calcium-based binders) or
Maria Dolores Sanchez-niño +2 more
exaly +3 more sources
Oral Phosphate Binders: History and Prospects
Bone, 2009The use of an oral phosphate binder is a promising and most practical strategy for the prevention of vascular calcification in patients with chronic kidney disease (CKD). To secure the safety: 1) the oral phosphate binder must not cause adverse effects in the gastrointestinal tract; 2) the oral phosphate binder should be non-absorbable or barely ...
Junichiro J Kazama
exaly +3 more sources
The Demise of Calcium-Based Phosphate Binders
Lancet, The, 2013Maria Dolores Sanchez-niño +1 more
exaly +3 more sources
Hyperphosphatemia and phosphate binders
American Journal of Health-System Pharmacy, 2005The pathophysiology of hyperphosphatemia associated with end-stage renal disease and treatment with phosphate binders are discussed.Phosphorus is an essential element necessary for the normal function of the human body, required for skeletal construction and synthesis of DNA, proteins, and adenosine triphosphate.
Jason J, Schucker, Kristina E, Ward
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The safety of phosphate binders
Expert Opinion on Drug Safety, 2006Disturbances of mineral metabolism occur during the early stages of chronic kidney disease. As renal function worsens, excess dietary phosphorus accumulates and blood levels increase, that can be clearly seen when the glomerular filtration rate has fallen below 30 ml/min/1.73 m2.
Jaume, Almirall +3 more
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