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Lanthanum: A Safe Phosphate Binder

Seminars in Dialysis, 2006
ABSTRACTAccumulation of inorganic phosphate due to renal functional impairment contributes to the increased cardiovascular mortality observed in dialysis patients. Phosphate plays a causative role in the development of vascular calcification in renal failure; treatment with calcium‐based phosphate binders and vitamin D can further increase the Ca × PO4
Veerle P, Persy   +4 more
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The Phosphate Binder Equivalent Dose

Seminars in Dialysis, 2011
AbstractPhosphate binders include calcium acetate or carbonate, sevelamer hydrochloride or carbonate, magnesium and lanthanum carbonate, and aluminum carbonate or hydroxide. Their relative phosphate‐binding capacity has been assessed in human, in vivo studies that have measured phosphate recovery from stool and/or changes in urinary phosphate excretion
John T, Daugirdas   +3 more
openaire   +2 more sources

Reasons for Phosphate Binder Discontinuation Vary by Binder Type

Journal of Renal Nutrition, 2014
Nonadherence to phosphate binder regimen is common among end-stage renal disease patients and contributes to elevated phosphorus levels. Pill burden, side effects, complex regimens, and cost all contribute to nonadherence. We retrospectively analyzed reasons for discontinuation in hemodialysis patients receiving treatment at a large U.S.
Steven, Wang   +5 more
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Phosphate binders: New products and challenges

Hemodialysis International, 2006
AbstractOptimal phosphate control in dialysis patients is extremely challenging. A growing awareness of the deleterious effect of mineral metabolism imbalances together with the lack of a satisfactory explanation for the exaggerated mortality rate in patients undergoing renal replacement therapy has led to a renewed effort to refine our approach to ...
A. Bellasi, L. Kooienga, G. A. Block
openaire   +2 more sources

Kaolin-phosphate binder

IV All-Russian (National) Scientific Conference "Achievements of Science and Technology"
A geopolymer kaolin phosphate binder has been synthesized based on metakaolin obtained from natural kaolin (750 o C) and 40 % orthophosphoric acid. The choice of aluminum silicate Al2O3·2SiO2 was due to the potential possibility of introducing a valuable component – mullite 3Al2O3·2SiO2 into the matrix in the process of heat treatment of a composite ...
N.V. Filatova   +2 more
openaire   +1 more source

Lanthanum carbonate: a new phosphate binder

Current Opinion in Nephrology & Hypertension, 2004
Hyperphosphatemia remains an important aspect in the management of end-stage renal disease patients. Consequently, there is a need for new, efficient and well-tolerated phosphate binders. In this review, a new phosphate-binding drug, lanthanum carbonate, with an attractive preclinical efficacy profile compared with existing binders, is discussed ...
Behets, G.J.   +3 more
openaire   +3 more sources

Calcium Carbonate Powder as a Phosphate Binder

ASAIO Transactions, 1989
With increasing recognition of problems regarding the use of aluminum hydroxide as a phosphate binder, calcium carbonate has become the medication of choice. Use of calcium has, however, frequently been associated with development of hypercalcemia. At this institution, calcium carbonate powder as a phosphate binder, examination of its efficacy, and the
D, Miller, T E, Taber, T F, Hegeman
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Comparison of Phosphate Binding Capacities of PA21, A Novel Phosphate Binder, with those of other Phosphate Binders in vitro and in vivo

Drug Research, 2016
The phosphate binding capacity of PA21, a novel phosphate binder, was compared with those of other phosphate binders in vitro and in vivo.1) For in vitro studies, PA21, sevelamer hydrochloride, lanthanum carbonate hydrate, calcium carbonate, and ferric citrate hydrate were incubated with a phosphate solution at 37°C for 2 h.
A, Yaguchi   +5 more
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Deformation of nonfired refractories on phosphate binders. 1. Specifics of nonfired refractories on phosphate binders

Refractories and Industrial Ceramics, 2006
Brief data on phosphate binders and materials based on them are provided. Compositions are selected to investigate their deformation in heating under load and creep.
S. S. Bakunov, U. Sh. Shayakhmetov
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Coatings based on phosphate binders

Glass and Ceramics, 2000
Hydroxyapatite coatings based on phosphate binders are described. Their adhesion characteristics, the TCLE, and the effect of the temperature on the strength of the material of the coatings are presented. Coatings based on phosphate binders can present interest for specialists in electrochemistry and medicine.
V. I. Vereshchagin   +2 more
openaire   +1 more source

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