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The Phosphate Binder Equivalent Dose
Seminars in Dialysis, 2011AbstractPhosphate binders include calcium acetate or carbonate, sevelamer hydrochloride or carbonate, magnesium and lanthanum carbonate, and aluminum carbonate or hydroxide. Their relative phosphate‐binding capacity has been assessed in human, in vivo studies that have measured phosphate recovery from stool and/or changes in urinary phosphate excretion
John T, Daugirdas +3 more
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Phosphate binders: New products and challenges
Hemodialysis International, 2006AbstractOptimal phosphate control in dialysis patients is extremely challenging. A growing awareness of the deleterious effect of mineral metabolism imbalances together with the lack of a satisfactory explanation for the exaggerated mortality rate in patients undergoing renal replacement therapy has led to a renewed effort to refine our approach to ...
A. Bellasi, L. Kooienga, G. A. Block
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Next-Generation Phosphate Binders: Focus on Iron-Based Binders
Drugs, 2014Phosphate excess is associated with increased mortality in patients with chronic kidney disease (CKD) and has recently been linked to accelerated aging. Oral phosphate binders are prescribed to patients with CKD to prevent absorption of dietary phosphate. Currently available binders have been associated with impaired outcomes (calcium-based binders) or
Dimitra, Nastou +6 more
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Reasons for Phosphate Binder Discontinuation Vary by Binder Type
Journal of Renal Nutrition, 2014Nonadherence to phosphate binder regimen is common among end-stage renal disease patients and contributes to elevated phosphorus levels. Pill burden, side effects, complex regimens, and cost all contribute to nonadherence. We retrospectively analyzed reasons for discontinuation in hemodialysis patients receiving treatment at a large U.S.
Steven, Wang +5 more
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Lanthanum carbonate: a new phosphate binder
Current Opinion in Nephrology & Hypertension, 2004Hyperphosphatemia remains an important aspect in the management of end-stage renal disease patients. Consequently, there is a need for new, efficient and well-tolerated phosphate binders. In this review, a new phosphate-binding drug, lanthanum carbonate, with an attractive preclinical efficacy profile compared with existing binders, is discussed ...
Behets, Geert +3 more
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Coatings based on phosphate binders
Glass and Ceramics, 2000Hydroxyapatite coatings based on phosphate binders are described. Their adhesion characteristics, the TCLE, and the effect of the temperature on the strength of the material of the coatings are presented. Coatings based on phosphate binders can present interest for specialists in electrochemistry and medicine.
V. I. Vereshchagin +2 more
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Oral phosphate binders: History and prospects
Bone, 2009The use of an oral phosphate binder is a promising and most practical strategy for the prevention of vascular calcification in patients with chronic kidney disease (CKD). To secure the safety: 1) the oral phosphate binder must not cause adverse effects in the gastrointestinal tract; 2) the oral phosphate binder should be non-absorbable or barely ...
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Medizinische Monatsschrift fur Pharmazeuten, 2016
Phosphate binders to treat hyperphosphataemia are part of the medication regime of every dialysis patient. Phosphate binders are taken with every meal (three times a day). Generally, the medication adherence rates of phosphate binders are very low. This is due to inconveniences like their bad taste or their size which makes them hard to swallow.
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Phosphate binders to treat hyperphosphataemia are part of the medication regime of every dialysis patient. Phosphate binders are taken with every meal (three times a day). Generally, the medication adherence rates of phosphate binders are very low. This is due to inconveniences like their bad taste or their size which makes them hard to swallow.
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Calcium Carbonate Powder as a Phosphate Binder
ASAIO Transactions, 1989With increasing recognition of problems regarding the use of aluminum hydroxide as a phosphate binder, calcium carbonate has become the medication of choice. Use of calcium has, however, frequently been associated with development of hypercalcemia. At this institution, calcium carbonate powder as a phosphate binder, examination of its efficacy, and the
D, Miller, T E, Taber, T F, Hegeman
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Selecting an Appropriate Phosphate Binder
Journal of Renal Nutrition, 1991Hyperphosphatemia in the renal patient is controlled by limiting dietary phosphorus and by prescribing a phosphate binder. Calcium compounds and aluminum compounds are currently used as phosphate binders. Selection of the appropriate compound may be based on physiological effect, patient benefit, and patient compliance. Considerations for each compound
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