Results 31 to 40 of about 26,534 (253)

Hyperphosphatemia and phosphate binders: effectiveness and safety [PDF]

open access: yesCurrent Medical Research and Opinion, 2013
In patients with kidney dysfunction hyperphosphatemia is more evident as renal failure progresses. It is related to increased FGF-23 levels, secondary hyperparathyroidism, and accelerated progressive vascular calcification. In CKD patients advanced coronary artery calcification is strongly associated with future cardiovascular events, cardiovascular ...
Rigas G, Kalaitzidis, Moses S, Elisaf
openaire   +2 more sources

Characterization and evaluation of acid-modified starch of Dioscorea oppositifolia (Chinese yam) as a binder in chloroquine phosphate tablets

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2013
Chinese yam (Dioscorea oppositifolia) starch modified by acid hydrolysis was characterized and compared with native starch as a binder in chloroquine phosphate tablet formulations.
Adenike Okunlola, Oluwatomi Akingbala
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

THE EFFECT OF TABLET MAKING ON THE MIGRATION OF CYANOCOBALAMIN FROM GRANULES DURING DRYING

open access: yesZagazig Journal of Pharmaceutical Sciences, 2007
The migration of cyanocobalamin upon drying of its wet granules was studied through the formulation of different granules using different diluents (lactose monohydrate and anhydrous dibasic calcium phosphate), different binders in different ...
Hassan EL-Sabbagh   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Research Status of Preparation and Properties in Inorganic Binder Based Anticorrosive Coatings [PDF]

open access: yesCailiao Baohu
Inorganic binders have become a research hotspot in the field of anti-corrosive coatings due to their advantages in economy, environmental friendliness and practicality.
WANG Zhongshan, ZHAI Zhiqiang, CHEN Tangjian, WU Yongling, LIU Mingming
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Physical and chemical properties of cement based on calcium phosphate suspensions [PDF]

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2017
The effect of phase composition, concentration of calcium phosphates suspensions and polymer binder on the physicochemical properties of calcium phosphate cements is found. It has been established that the introduction of monetite and polymers (polyvinyl
O.N. Musskaya   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Impact of vascular calcification on cardiovascular mortality in hemodialysis patients: clinical significance, mechanisms and possible strategies for treatment

open access: yesRenal Replacement Therapy, 2017
Vascular calcification has now been recognized as a major problem in dialysis patients because of its strong influence on the prognosis. Along with the regulatory failure of calcification-inhibitory system, active phenotypic change of vascular smooth ...
Takayasu Ohtake, Shuzo Kobayashi
doaj   +1 more source

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