Results 121 to 130 of about 23,252 (243)
Serum calcium levels after 8 weeks administration of calcium-based phosphate binders.
Serum calcium levels after 8 weeks administration of calcium-based phosphate binders.
Han Zhang (110653) +5 more
core +1 more source
BackgroundHyperphosphatemia poses a significant risk for cardiovascular diseases and mortality in hemodialysis patients. Non-adherence to phosphate binders and a low-phosphate diet behavior contribute to this issue.
Arrom Thongsunti +7 more
doaj +1 more source
Impact of phosphate binders on quality of life in dialysis patients: Results from the prospective Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes study. [PDF]
Colombijn JMT +6 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Development tendencies of moulding and core sands [PDF]
Further development of the technology for making moulding and core sands will be strictly limited by tough requirements due to protection of the natural environment.
Stanislaw M. Dobosz1 +2 more
doaj
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
An introduction to phosphate binders for the treatment of hyperphosphatemia in patients with chronic kidney disease. Chronic kidney disease has the potential to induce sequelae that can have severe and mortal outcomes.
Friedman, Eli A.
core +1 more source
A Randomized Trial of Tenapanor and Phosphate Binders as a Dual-Mechanism Treatment for Hyperphosphatemia in Patients on Maintenance Dialysis (AMPLIFY). [PDF]
Pergola PE +3 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Kimberly F Farrand,1 J Brian Copley,1 Jamie Heise,1 Moshe Fridman,2 Michael S Keith,1 Lynne Poole3 1Shire, Wayne, PA, USA; 2AMF Consulting, Los Angeles, CA, USA; 3Shire, Basingstoke, UK Abstract: The purpose of this study was to conduct a retrospective ...
Farr +6 more
core

