Results 111 to 120 of about 23,252 (243)
Forest plot of sevelamer vs. calcium phosphate binders on ACS change.
, 2015 Forest plot of sevelamer vs. calcium phosphate binders on ACS change.
Yongming Zhou (429711) +6 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Effect of the P/Al Molar Ratio and Heating Rate on the Composi-Tion of Alumino-Phosphate Binders. [PDF]
Materials (Basel), 2022 Tricot G +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Phosphate Binders in Refractory Application
The doctoral thesis is focused on the study, research and development of refractories with phosphate bonding. Primary motivation is preparation of phosphate-based binders that can be applied for non-shaped insulating material fabricated by “in situ ...
Švec, Jiří
core
Forest plot of sevelamer vs. calcium phosphate binders on CACS change.
, 2015 Forest plot of sevelamer vs. calcium phosphate binders on CACS change.
Yongming Zhou (429711) +6 more
core +1 more source
Effect of Phosphate Binders and a Dietary Iron Supplement on the Pharmacokinetics of a Single Dose of Vadadustat in Healthy Adults. [PDF]
Clin Pharmacol Drug Dev, 2022 Paulson SK +4 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Serum PTH levels after 8 weeks administration of calcium-based phosphate binders.
, 2015 Serum PTH levels after 8 weeks administration of calcium-based phosphate binders.
Han Zhang (110653) +5 more
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source