Results 61 to 70 of about 272,636 (196)
Regulation of Phosphate Transporters and Novel Regulator of Phosphate Metabolism
Endocrines, 2023 Phosphorus is essential for all living organisms. It plays an important role in maintaining biological functions, such as energy metabolism, cell membrane formation, and bone mineralization.
Megumi Koike +4 more
doaj +1 more source
Ancient and recent collisions revealed by phosphate minerals in the Chelyabinsk meteorite [PDF]
arXiv, 2021 The collision history of asteroids is an important archive of inner Solar System evolution. Evidence for these collisions is brought to Earth by meteorites, which can preserve impact-reset radioisotope mineral ages. However, as meteorites often preserve numerous mineral ages, their interpretation is controversial. Here, we combine analysis of phosphate
arxiv
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
mSphere, 2023 The fungal pathogen Candida albicans must acquire phosphate to colonize, infect, and proliferate in the human host. C. albicans has four inorganic phosphate (Pi) transporters, Pho84 being the major high-affinity transporter; its cells can also use ...
William R. King +6 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Journal of Pediatric Critical Care, 2019 Phosphate plays an important role in cell structure and metabolism. Less than 1% of phosphate is in circulating serum and maintained within narrow range by hormones PTH, calcitonin, FGF23, vitamin D.
Kundan Mittal
doaj +1 more source
Change of Hydration Patterns upon RNA Melting Probed by Excitations of Phosphate Backbone Vibrations [PDF]
, 2020 The water hydration shell has decisive impact on the structural and functional properties of RNA. Changes of RNA structure upon melting and in biochemical processes are accompanied by a change of hydration patterns, a process which is barely characterized.
arxiv +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Frontiers in Fungal BiologyThere is an urgent need for new antifungal drugs to treat invasive fungal diseases. Unfortunately, the echinocandin drugs that are fungicidal against other important fungal pathogens are ineffective against Cryptococcus neoformans, the causative agent of
Xianya Qu +14 more
doaj +1 more source
Role of homeostasis in learning sparse representations [PDF]
Neural Computation, Massachusetts Institute of Technology Press
(MIT Press), 2010, 22 (7), pp.1812-36, 2007 Neurons in the input layer of primary visual cortex in primates develop edge-like receptive fields. One approach to understanding the emergence of this response is to state that neural activity has to efficiently represent sensory data with respect to the statistics of natural scenes.
arxiv +1 more source