Results 91 to 100 of about 1,014,517 (352)

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Nature Communications, 2016
Histone deacetylases (HDACs) 1, 2 and 3 form the catalytic subunit of several large transcriptional repression complexes. Unexpectedly, the enzymatic activity of HDACs in these complexes has been shown to be regulated by inositol phosphates, which bind ...
Peter J. Watson, C. J. Millard, Andrew M. Riley, Naomi S. Robertson, L. C. Wright, H. Y. Godage, S. Cowley, Andrew G. Jamieson, Barry V. L. Potter, John W. R. Schwabe   +9 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Comprehensive Dissolution Study on Two Double Ce(IV) Phosphates with Evidence of Secondary CeO₂ Nanoparticle Formation

Molecules
Herein, we present a comprehensive study on the dissolution behaviour of two sodium–cerium(IV) phosphate phases synthesised hydrothermally from CeO2 nanoparticles: crystalline Na2Ce(PO4)2 and nanocrystalline NaCe2(PO4)3.
Anastasiia L. Listova, Anastasiia S. Kuzenkova, Mikhail A. Gerasimov, Elizaveta S. Kulikova, Roman D. Svetogorov, Daniil A. Novichkov, Alexei A. Averin, Vasiliy O. Yapaskurt, Anna Yu. Romanchuk, Stepan N. Kalmykov, Tatiana V. Plakhova   +10 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

METHODS FOR ASSESSMENT OF INTERNAL NUTRIENT LOAD OF WATER BODIES (A REVIEW)

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2019
Internal nutrient load of freshwater bodies is a key element in the study and modeling of the processes of eutrophication of lakes and storage reservoirs.
Yury Datsenko
doaj   +1 more source

Speciation of phosphorus in a fertilized, reduced-till soil system: in-field treatment incubation study [PDF]

, 2012
Citation: Khatiwada, Raju, Ganga M. Hettiarachchi, David B. Mengel, and Mingwei Fei. “Speciation of Phosphorus in a Fertilized, Reduced-Till Soil System: In-Field Treatment Incubation Study.” Soil Science Society of America Journal 76, no. 6 (2012): 2006–
Arai, Beauchemin, Benbi, Bordoli, Bray, Bremner, Chapman, Combs, Dalas, David B. Mengel, Fixen, Foth, Frank, Ganga M. Hettiarachchi, Hansen, Hanson, Hedley, Helyar, Hesterberg, Hettiarachchi, Hingston, Hingston, Hobbs, Holloway, Hsu, Khare, Kilmer, Lawton, Lindsay, Lombi, Lombi, Malinowski, Mallarino, Marcus, McBeath, McLean, Mehlich, Menon, Mingwei Fei, Moody, Murphy, Myers, Nachtegaal, Oh, Peak, Pierzynski, Pierzynski, Raju Khatiwada, Ravel, Rietra, Saggar, Salcedo, SAS Institute, Sato, Schwab, Schwertmann, Sharpley, Sharpley, Simard, Sims, Soil Survey Laboratory Staff, Sposito, Thomas, Toor, Warncke, Watanabe, Wateson, Whitney   +67 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

High Zn content of Randall's plaque: A μ-X-ray fluorescence investigation [PDF]

, 2011
Kidney stone disease, or nephrolithiasis, is a common ailment. Among the different risk factors usually associated with nephrolithiasis are dehydration, metabolic defects (especially with regard to calcium and oxalate).
Albouy, Pierre-Antoine, Bazin, Dominique, Carpentier, Xavier, Combes, Christèle, Daudon, Michel, Foy, Eddy, Mazouyes, Aurélie, Rouzière, Stephan   +7 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Mineral resources of Vietnam [PDF]

Acta Montanistica Slovaca, 2000
Vietnam je bohatý na nerastné suroviny, ktoré sa nachádzajú prevažne na severe krajiny. Ložiská bauxitov, fosfátov, vzácnych zemín (REE), majú svetový význam.
Kušnír Imrich
doaj