Results 101 to 110 of about 138,912 (309)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Phosphorus and Fluorine - The Union for Bioregulators [PDF]

open access: yesKemija u Industriji, 2007
The review demonstrates the very high efficiency and usefulness of the fluorine-phosphorus combination in order to synthesize organic molecules for purposes of modern life science.
Romanenko, V., Kukhar, V.
doaj  

Comprehensive effect of Al2O3 content and binary basicity on the enrichment mechanism of phosphates in quenched steelmaking slags

open access: yes工程科学学报, 2016
A comprehensive effect of Al2O3 content and binary basicity B on the enrichment behavior of phosphates in rapidly quenched CaO-SiO2-FeO-P2O5-Fe2O3-Al2O3 steelmaking slags was investigated through thermodynamic calculations and experimental determination.
LI Jin-yan   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Antimicrobial and Antioxidant Properties of Phosphates Used in Meat Products [PDF]

open access: yes, 2017
Phosphates are widely used as food additives in meat products to increase the water-holding capacity, reduce the cooking loss and improve the textural properties.
Azim Şimşek, Birol Kılıç
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A study of shear viscosity of interfacial films containing alkyl metal phosphates

open access: yes, 2004
Experimental data are presented to show the influence of alkyl metal phosphates, Shengli resin fraction, and NaCl, on the shear viscosity of interfacial films and the stability of emulsions.
Li, MY   +11 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Copper-substituted tricalcium phosphates [PDF]

open access: yes, 2016
© 2016, Pleiades Publishing, Ltd.Copper-substituted tricalcium phosphates (CuTCP) with different copper contents were developed using precipitation of copper-containing amorphous calcium phosphates (ACP) from salt solutions followed by heat treatment ...
Davydova G.   +12 more
core  

The structural chemistry of phosphates

open access: yes, 1971
La chimie structurale des phosphates. On a maintenant des informations sur la structure cristalline de plus de trois cents composés avec liaison P-O.
Corbridge, Derek E. C.
core   +1 more source

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