Results 101 to 110 of about 138,912 (309)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Phosphorus and Fluorine - The Union for Bioregulators [PDF]
The review demonstrates the very high efficiency and usefulness of the fluorine-phosphorus combination in order to synthesize organic molecules for purposes of modern life science.
Romanenko, V., Kukhar, V.
doaj
A comprehensive effect of Al2O3 content and binary basicity B on the enrichment behavior of phosphates in rapidly quenched CaO-SiO2-FeO-P2O5-Fe2O3-Al2O3 steelmaking slags was investigated through thermodynamic calculations and experimental determination.
LI Jin-yan +3 more
doaj +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Antimicrobial and Antioxidant Properties of Phosphates Used in Meat Products [PDF]
Phosphates are widely used as food additives in meat products to increase the water-holding capacity, reduce the cooking loss and improve the textural properties.
Azim Şimşek, Birol Kılıç
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
A study of shear viscosity of interfacial films containing alkyl metal phosphates
Experimental data are presented to show the influence of alkyl metal phosphates, Shengli resin fraction, and NaCl, on the shear viscosity of interfacial films and the stability of emulsions.
Li, MY +11 more
core +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Copper-substituted tricalcium phosphates [PDF]
© 2016, Pleiades Publishing, Ltd.Copper-substituted tricalcium phosphates (CuTCP) with different copper contents were developed using precipitation of copper-containing amorphous calcium phosphates (ACP) from salt solutions followed by heat treatment ...
Davydova G. +12 more
core
The structural chemistry of phosphates
La chimie structurale des phosphates. On a maintenant des informations sur la structure cristalline de plus de trois cents composés avec liaison P-O.
Corbridge, Derek E. C.
core +1 more source

