Results 121 to 130 of about 125,203 (314)

Calcium Phosphates for Clinical Application with Variable Phase Composition: Synthesis and Characterization

open access: yes
Hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) represent the main types of calcium phosphates use for bone and dental surgery. HAp is thermodynamically the most stable phase in physiological conditions and has the ability to form direct chemical
Plūduma, Liene   +4 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Impacts of Agricultural Practices (Pesticides and Fertilizers) and Amalnala Stream on Amalnala Lake in Gadchandur, India

open access: yesJournal of Pure and Applied Microbiology
Amalnala lake is situated in the Gadchandur town of Chandrapur district in Maharashtra, India. The lake water was turning green in colour in the month of september.
Utkarsh Ravindra Moon   +2 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Antimicrobial and Antioxidant Properties of Phosphates Used in Meat Products

open access: yes, 2017
Phosphates are widely used as food additives in meat products to increase the water-holding capacity, reduce the cooking loss and improve the textural properties.
Azim Şimşek, Birol Kılıç
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Fourier Transform Infrared Spectra of Technologically Modified Calcium Phosphates

open access: yes
Calcium phosphate powders were synthesized by wet-chemical precipitation method using CaCO3 and H3PO4 as starting materials. Influence of technological parameters on chemical composition of as-prepared and thermal treated calcium phosphate samples were ...
Borodajenko, Natālija   +4 more
core  

Les phosphates de Gafsa

open access: yes, 1957
Brunet Roger. Les phosphates de Gafsa. In: L'information géographique, volume 21, n°4, 1957. pp.
Brunet, Roger
core   +1 more source

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