Results 61 to 70 of about 138,912 (309)

Photoredox-Catalyzed Deformylative 1,4-Addition of 2′-Deoxy-5′‑O‑phthalimido­nucleosides for Synthesis of 5′-Carba Analogs of Nucleoside 5′-Phosphates

open access: yes, 2018
A concise approach for the synthesis of the 5′-carba analogs of nucleoside 5′-phosphates from 2′-deoxy-5′-O-phthalimidonucleosides by a visible-light-mediated deformylative 1,4-addition was developed. This method enabled rapid and facile generation of 4′-
Yoshiyuki Hari (1489759)   +3 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Acidosis and Phosphate Directly Reduce Myosin’s Force-Generating Capacity Through Distinct Molecular Mechanisms

open access: yesFrontiers in Physiology, 2018
Elevated levels of the metabolic by-products, including acidosis (i.e., high [H+]) and phosphate (Pi) are putative agents of muscle fatigue; however, the mechanism through which they affect myosin’s function remain unclear. To elucidate these mechanisms,
Mike Woodward, Edward P. Debold
doaj   +1 more source

PHOSPHATIC DIABETES. [PDF]

open access: yesThe Lancet, 1900
n ...
openaire   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Cements of doped calcium phosphates for bone implantation [PDF]

open access: yes, 2009
Doutoramento em Ciência e Engenharia de MateriaisO principal objectivo deste estudo foi o desenvolvimento de cimentos à base de fosfatos de cálcio dopados com Mg, Sr e Zn, para aplicações clínicas.
Pina, Sandra Cristina de Almeida
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Thermal stability of phosphate coatings on steel

open access: yesMetalurgija, 2015
The work was validated thermal stability of zinc, manganese and tri-cations phosphate coatings on steel, made from commercial phosphating bath type Pragofos.
P. Pokorny   +4 more
doaj  

Phosphate sensing [PDF]

open access: yesCurrent Opinion in Nephrology and Hypertension, 2009
To discuss findings suggesting the presence of a phosphate-sensing mechanism in the various organs and the presence of a novel intestinal effector that alters renal phosphate excretion after the ingestion of a phosphate-containing meal.Although phosphate homeostasis is controlled by a variety of hormones (such as parathyroid hormone and 1,25 ...
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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