Results 51 to 60 of about 141,131 (304)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Nutrient analysis in estuarine water. Effect of salinity

Ciencias Marinas, 2003
The continous flow autoanalyzer is an instrument commonly used for nutrient analysis in coastal laboratories and oceanographic vessels. The determination of micronutrient concentrations (ammonium, nitrites, nitrates, silicates and phosphates) makes it ...
M Arjonilla, J Blasco
doaj   +1 more source

Study on the structure of phosphorus-containing zeolite anionic nanoporous materials

Хімія, фізика та технологія поверхні, 2022
Phosphates are specific compounds of the composition of living organisms, that play a special role in plant and animal life. The skeleton of most living organisms consists mainly of calcium, sodium, magnesium and other phosphates.
G. P. Tsintskaladze, T. M. Sharashenidze, L. G. Eprikashvili, M. G. Zautashvili, T. N. Kordzakhia, M. A. Dzagania   +5 more
doaj   +1 more source

Phosphate Sensing [PDF]

Advances in Chronic Kidney Disease, 2011
Human phosphate homeostasis is regulated at the level of intestinal absorption of phosphate from the diet, release of phosphate through bone resorption, and renal phosphate excretion, and involves the actions of parathyroid hormone, 1,25-dihydroxy-vitamin D, and fibroblast growth factor 23 to maintain circulating phosphate levels within a narrow normal
Clemens, Bergwitz, Harald, Jüppner
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Photoredox-Catalyzed Deformylative 1,4-Addition of 2′-Deoxy-5′‑O‑phthalimido­nucleosides for Synthesis of 5′-Carba Analogs of Nucleoside 5′-Phosphates

, 2018
A concise approach for the synthesis of the 5′-carba analogs of nucleoside 5′-phosphates from 2′-deoxy-5′-O-phthalimidonucleosides by a visible-light-mediated deformylative 1,4-addition was developed. This method enabled rapid and facile generation of 4′-
Yoshiyuki Hari (1489759), Airi Kimura (5720477), Takashi Osawa (1489765), Yuta Ito (1362546)   +3 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

MINERAL FORMS OF PHOSPHORUS IN OOIDAL IRON ORES OF THE MARSYATY DEPOSIT (NORTHERN URALS) [PDF]

Минералогия
Horizons enriched in phosphorus are identified in ooidal ironstones underlying the oxidecarbonate manganese ores of the Marsyaty deposit (Northern Urals). The maximum P2O5 content reaches 6.37 wt. % in a quartz sandstone interbed with ooids consisting of
E.V. Belogub, K.A. Novoselov, A.I. Brusnitsyn, M.A. Rassomakhin, V.N. Bocharov   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source