Results 151 to 160 of about 47,232 (289)

Tks4‐Targeted Gene Therapy Inhibited White Adipocyte Hypertrophy in Mice

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Tks4 knockout or knockdown by AAV mediated shRNA both successfully restricted adipocyte hypertrophy in high fat diet. The reduction of TAG was validated by biochemistry and lipidomics analyses. This study suggested a potential of Tks4 targeted therapy in obesity intervention. ABSTRACT Obesity is one of the most prevalent public health issues worldwide,
Meng Tian   +5 more
wiley   +1 more source

Prostacyclin production in rat aortic smooth muscle cells: role of protein kinase C, phospholipase D and cyclooxygenase-2 expression [PDF]

open access: yes, 2017
Objective: The present study was designed to investigate the role of protein kinase C (PKC) and phospholipase D (PLD) in angiotensin II (AngII)- and phorbol ester (PMA)-induced cyclooxygenase-2 (COX-2) expression and prostacyclin (PGI2) production in rat
Dubouloz, Frédérique   +3 more
core  

Supplementary Figure S5 from mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells

open access: gold, 2023
Tra-Ly Nguyen   +22 more
openalex   +1 more source

Regulation of phosphatidic acid phosphatase

open access: yesThe FASEB Journal, 2010
Phosphatidic acid phosphatase (PAP) catalyzes the dephosphorylation of phosphatidic acid (PA) to yield diacylglycerol (DAG) and P i . The DAG generated in the reaction is used for the synthesis of triacylglycerol (TAG), and for the synthesis of ...
openaire   +1 more source

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