Results 21 to 30 of about 4,293 (162)

Lecithin:cholesterol acyltransferase: role of N-linked glycosylation in enzyme function.

open access: yesBiochemical Journal, 1993
Lecithin:cholesterol acyltransferase (LCAT; phosphatidylcholine-sterol acyltransferase, EC 2.3.1.43) is a glycoprotein which is responsible for the formation of cholesteryl ester in plasma. The carbohydrate content has been estimated to be approx. 25% of
Karmin   +4 more
semanticscholar   +1 more source

Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses

open access: yesCommunications Biology, 2021
The risks of non-alcoholic fatty liver disease (NAFLD) include obese and non-obese stresses such as chronic hepatitis C virus (HCV) infection, but the regulatory determinants remain obscure.
Hung-Yu Sun   +4 more
semanticscholar   +2 more sources

Isolation and properties of porcine lecithin:cholesterol acyltransferase.

open access: yesEuropean Journal of Biochemistry, 1986
Lecithin: cholesterol acyltransferase (LCAT, phosphatidylcholine: sterol O-acyltransferase, EC 2.3.1.43) was purified approximately 20 000-fold from pig plasma by ultracentrifugation, phenyl-Sepharose and hydroxyapatite chromatography.
G. Knipping
semanticscholar   +1 more source

Comprehensive Analysis of Sterol O-Acyltransferase 1 as a Prognostic Biomarker and Its Association With Immune Infiltration in Glioma

open access: yesFrontiers in Oncology, 2022
Metabolic reprogramming is a hallmark of glioma, and sterol O-acyltransferase 1 (SOAT1) is an essential target for metabolic therapy. However, the prognostic value of SOAT1 and its association with immune infiltration has not been fully elucidated. Using
Xuyan Guo   +7 more
semanticscholar   +1 more source

Sterol O-Acyltransferase Inhibition Ameliorates High-Fat Diet-Induced Renal Fibrosis and Tertiary Lymphoid Tissue Maturation after Ischemic Reperfusion Injury

open access: yesInternational Journal of Molecular Sciences, 2022
Metabolic syndrome is associated with the development of chronic kidney disease (CKD). We previously demonstrated that aged kidneys are prone to developing tertiary lymphoid tissues (TLTs) and sustain inflammation after injury, leading to CKD progression;
Yuki Ariyasu   +5 more
semanticscholar   +1 more source

Diagnosis of epithelial ovarian cancer using a combined protein biomarker panel

open access: yesBritish Journal of Cancer, 2019
An early detection tool for EOC was constructed from analysis of biomarker expression data from serum collected during the UKCTOCS. This study included 49 EOC cases (19 Type I and 30 Type II) and 31 controls, representing 482 serial samples spanning ...
Matthew Russell   +9 more
semanticscholar   +1 more source

Sex and hormonal status influence plasma lipid responses to psyllium.

open access: yesAmerican Journal of Clinical Nutrition, 2001
BACKGROUND The primary mechanisms by which soluble fiber lowers plasma cholesterol are well known. However, specific effects of fiber on lipoprotein metabolism and how sex and hormonal status influence these effects are not well defined.
Sonia Vega-López   +2 more
semanticscholar   +1 more source

Functional Analysis of Sterol O-Acyltransferase Involved in the Biosynthetic Pathway of Pachymic Acid in Wolfiporia cocos

open access: yesMolecules, 2021
Pachymic acid from Wolfiporia cocos possesses important medicinal values including anti-bacterial, anti-inflammatory, anti-viral, invigorating, anti-rejection, anti-tumor, and antioxidant activities.
Wenjun Zhu   +7 more
semanticscholar   +1 more source

Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations [PDF]

open access: yes, 2011
Phospho- and sphingolipids are crucial cellular and intracellular compounds. These lipids are required for active transport, a number of enzymatic processes, membrane formation, and cell signalling.
A Cecile J W Janssens   +57 more
core   +11 more sources

Molecular mechanism of dietary phospholipid requirement of Atlantic salmon, Salmo salar, fry [PDF]

open access: yes, 2015
The phospholipid (PL) requirement in fish is revealed by enhanced performance when larvae are provided PL-enriched diets. To elucidate the molecular mechanism underlying PL requirement in Atlantic salmon, Salmo salar, were fed a minimal PL diet and ...
Carmona-Antoñanzas, Greta   +3 more
core   +1 more source

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