Advanced Science, EarlyView.In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen +17 more
wiley +1 more source
Studies of cationic amphiphilic drug catalysed membrane degradation [PDF]
, 2007 Imperial Users ...
Sebai, Sarra C., Sebai, Sarra C.
core
Combined Monte Carlo and Molecular Dynamics Simulation of Fully Hydrated Dioleyl and Palmitoyl-oleyl Phosphatidylcholine Lipid Bilayers [PDF]
, 1999 S.-W. Chiu +3 more
openalex +1 more source
Altered phosphatidylcholine metabolism in children with atopic dermatitis [PDF]
, 2023 So-Yeon Lee +3 more
openalex +1 more source
Advanced Science, EarlyView.Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan +6 more
wiley +1 more source
Electrophysiological characteristics of cationic single-channel formed by incorporation of amphotericin b in bilayer lipid membrane [PDF]
, 2016 BACKGROUND AND OBJECTIVE: Amphotericin B (AmB) is the main antibiotic of polyene type, which is widely used in the treatment of systemic fungal infections.
Ashrafpour, M. +2 more
core
Giant vesicles at the prolate-oblate transition: A macroscopic bistable system
, 1996 Giant phospholipid vesicles are shown to exhibit thermally activated transitions between a prolate and an oblate shape on a time scale of several seconds.
Duwe H. P. +9 more
core +1 more source
Correlation of fatty acid composition of adipose tissue lipids and serum phosphatidylcholine and serum concentrations of micronutrients with disease duration in rheumatoid arthritis. [PDF]
, 1990 L. Jacobsson +3 more
openalex +1 more source
Advanced Science, EarlyView.Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen +9 more
wiley +1 more source
Potential antioxidant activity of pomegranate peel and seed extracts and synergism with added phenolic antioxidants in a liposome system: a preliminary study [PDF]
, 2014 peer-reviewedThis study describes the use of liposomes as biological membrane models to evaluate the potential of natural antioxidants as inhibitors of lipid peroxidation.
Altunkaya, A.
core