Results 121 to 130 of about 155,795 (339)

Cholesterol esterase action on human high density lipoproteins and inhibition studies: detection by MALDI-TOF MS

Journal of Lipid Research, 2005
The modification of lipoproteins by lipolytic enzymes such as cholesterol esterase (CEase) is assumed to play an important role in the pathogenesis of atherosclerosis. However, details of the activation and inhibition of CEase are still unknown.
Olaf Zschörnig, Markus Pietsch, Rosemarie Süß, Jürgen Schiller, Michael Gütschow   +4 more
doaj   +1 more source

Integrating Metabolic Modulation and Nanomedicine for Cancer Immunotherapy

Advanced Science, EarlyView.
Metabolic rewiring in cancer is mapped across glucose, amino acid, lipid, nucleotide, and mitochondrial pathways, with emphasis on immune regulation. The review integrates mechanisms linking these pathways to tumor progression and therapy resistance, and profiles nanomaterial platforms that both deliver therapeutics and actively reprogram ...
Xiaosu Zhou, Ruibing Deng, Zunde Liao, Xiaoyu Huang, Junting Huang, Hanlou Yang, Kam W. Leong, Yiling Zhong   +7 more
wiley   +1 more source

Headgroup conformation and lipid--cholesterol association in phosphatidylcholine vesicles: a 31P(1H) nuclear Overhauser effect study. [PDF]

, 1975
Philip L. Yèagle, William Hutton, C.H. Huang, R. Bruce Martin   +3 more
openalex   +1 more source

EGFR Targeted Liposomal PROTAC Assisted With Epigenetic Regulation as an Efficient Strategy for Osimertinib‐Resistant Lung Cancer Therapy

Advanced Science, EarlyView.
In this study, an EGFR lipoSM PROTACs (GM‐protac), which can achieve efficient EGFR degradation and HDACi delivery, is developed. It is found that GM‐protac can both block EGFR‐dependent pathways and bypass the HDAC signaling pathway. Meanwhile, both display obvious tumor inhibition with negligible toxicity in EGFR‐TKI‐resistant lung cancer animal ...
Dongyuan Wang, Yajing Liu, Ying Chen, Chuan Dai, Wenzhu Hu, Jinyan Han, Zigang Li, Feng Yin, Yu Zhang, Chen Shi   +9 more
wiley   +1 more source

Caracterização da pureza de fosfatidilcolina da soja através de RMN de ¹H e de 31P Characterization of soybean phosphatidylcholine purity by ¹H and 31P NMR

Química Nova, 2008
A strategy is proposed to evaluate the purity of phosphatidylcholine from soybean lecithin, obtained by extraction or column chromatography, using the integrals ratio of ¹H NMR spectra.
Omar Mertins, Marcelo Sebben, Paulo Henrique Schneider, Adriana Raffin Pohlmann, Nádya Pesce da Silveira   +4 more
doaj   +1 more source

The Structure of Lipids and Proteins Studied by Attenuated Total Reflection (ATR) Infrared Spectroscopy II. Oriented Layers of a Homologous Series: Phosphatidylethanolamine to Phosphatidylcholine [PDF]

, 1977
U. P. Fringeli
openalex   +1 more source

Structural properties and Raman spectroscopy of lipid Langmuir monolayers at the air-water interface

, 2010
Spectra of octadecylamine (ODA) Langmuir monolayers and egg phosphatidylcholine (PC)/ODA-mixed monolayers at the air-water interface have been acquired.
Aroca., Bohdana, Chamberlain, Chazalet, Curtis, Fendler, Frank, Greenhall, Guo, Hill, Hongxin Dang, Honig, Huang, Ignes-mullol, Kobayashi, Lee, Lin, Lin-Vien, Maquelin, Marg, Meldrum, Michota, Moskovits, Nie, Patil, Peter, Pettinger, Rivas, Roberts, Samned, Schoefisch, Shuxi Dai, Song, Spiker, Taylor, Thompson, Tollner, Tsen, Wong, Xingtang Zhang, Yabin Huang, Young, Zuliang Du   +42 more
core   +1 more source

Enzalutamide‐Resistant STEAP4+ MyoCAF Secrete Phosphatidylcholine to Foster Progression by Activating Stemness in Hormone‐Sensitive Prostate Cancer

Advanced Science, EarlyView.
Expanding enzalutamide (ENZ) use in hormone‐sensitive prostate cancer (HSPC) faces resistance. Single‐cell profiling identifies therapy‐resistant STEAP4+ myofibroblastic cancer‐associated fibroblast (SETAP4+ myoCAF). These myoCAFs drive resistance via TFE3‐mediated autophagy and PCYT1A‐led phosphatidylcholine overproduction, creating a phospholipid ...
Wenhao Wang, Jing Zhao, Tiewen Li, Guangjian Fan, Jianong Zhang, Chenghao Zheng, Zhiwen Xie, Yu Zhang, Chengling Feng, Tianyu Cao, Jianyin Li, Guomin Ju, Di Cui, Shujie Xia, Bangmin Han   +14 more
wiley   +1 more source

Structural Changes Of Dha-Containing Phospholipids By K+ And Na+ Cations In Nerve Cell Membranes [PDF]

, 2010
Understanding the structure and dynamics of a docosa hexaenoic acid (DHA) containing phospholipid monomer within membranes is essential for recognizing the bilayer function in central nervous system. It has been recognized that the electrical impulses in
Khodayari, N., Mollaamin, F., Monajjemi, M.   +2 more
core  

Lactate Dehydrogenase C4 Accelerates Triple‐Negative Breast Cancer Progression by Promoting Acetyl‐CoA Acyltransferase 2 Lactylation to Increase Free Fatty Acid Accumulation

Advanced Science, EarlyView.
Diagram of the reprogramming of FA metabolism mediated by LDHC4‐induced ACAA2 activity to promote TNBC progression. LDHC4 drives TNBC progression by enhancing ACAA2‐mediated fatty acid production. The resulting accumulation of FFAs stimulates autophagy and accelerates cell cycle progression, thereby promoting tumor growth.
Zhaolei Cui, Chaoqiang Zheng, Yingying Lin, Zhenzhou Xiao, Yanhong Li, Wei Peng, Shijie He, Anyang Li, Xiufeng Wu, Yan Chen, Yang Sun   +10 more
wiley   +1 more source