Results 121 to 130 of about 158,967 (337)

Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy

Advanced NanoBiomed Research, EarlyView.
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li, Yibo He, Yang Zhang, Lining Arnold Ju, Yao Wang, Jianxuan Zhou, Yinying Chai, Xuhui Hui, ShiYuan Tong, Si Zhang, Yanli Tan, Yinyan Wang   +11 more
wiley   +1 more source

PHARMACOEPIDEMIOLOGICAL EVALUATION OF HEPATOTROPIC THERAPY IN REAL CLINICAL PRACTICE

Фармакоэкономика, 2015
Chronic liver diseases are a serious problem and a common cause of suffering and death in all countries. Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver diseases.
D. V. Blinov, U. V. Zimovina, T. I. Ushakova   +2 more
doaj   +1 more source

Curvature properties of novel forms of phosphatidylcholine with branched acyl chains [PDF]

, 2000
Richard M. Epand, Richard M. Epand, Anthony Decicco, Dieter Schwarz   +3 more
openalex   +1 more source

Zweikanal‐Fluoreszenz‐Assays mit supramolekularen Wirt/Farbstoff‐Reporterpaaren zur Kartierung der Membranaktivität von Peptiden

Angewandte Chemie, EarlyView.
Membranaktive Peptide (MAPs) wie zellpenetrierende Peptide (CPPs) und antimikrobielle Peptide (AMPs) können Lipidmembranen durchdringen und Membranporen bilden. Die Kombination aus einem Farbstoff‐Efflux‐Assay und einem supramolekularen Tandem‐Membran‐Assay in einem Zweikanalformat ermöglicht eine fortgeschrittene mechanistische Charakterisierung und ...
Mohammad A. Alnajjar, Sandra N. Schöpper, Malavika Pramod, Thomas Reingolz, Lina Müller, Justin Neumann, Mohamed Nilam, Werner M. Nau, Andreas Hennig   +8 more
wiley   +1 more source

Studies of cationic amphiphilic drug catalysed membrane degradation [PDF]

, 2007
Imperial Users ...
Sebai, Sarra C., Sebai, Sarra C.
core  

Insight into the Putative Specific Interactions between Cholesterol, Sphingomyelin, and Palmitoyl-Oleoyl Phosphatidylcholine [PDF]

, 2006
Jussi Aittoniemi, Perttu Niemelä, M. Hyvönen, Mikko Karttunen, Ilpo Vattulainen   +4 more
openalex   +1 more source

Dual‐Channel Fluorescence Assays with Supramolecular Host‐Dye Reporter Pairs for Membrane Activity Mapping of Peptides

Angewandte Chemie International Edition, EarlyView.
Membrane‐active peptides (MAPs) such as cell‐penetrating peptides (CPPs) and antimicrobial peptides (AMPs) can translocate across lipid membranes and create membrane pores. The combination of a dye efflux and a supramolecular tandem membrane assay in a dual‐channel format enables an advanced mechanistic characterization and an exploration of the ...
Mohammad A. Alnajjar, Sandra N. Schöpper, Malavika Pramod, Thomas Reingolz, Lina Müller, Justin Neumann, Mohamed Nilam, Werner M. Nau, Andreas Hennig   +8 more
wiley   +1 more source

Molecular theory of hydrophobic mismatch between lipids and peptides

, 2001
Effects of the mismatch between the hydrophobic length, d, of transmembrane alpha helices of integral proteins and the hydrophobic thickness, D_h, of the membranes they span are studied theoretically utilizing a microscopic model of lipids. In particular,
Daniel Duque, Froud R. J., Kirill Katsov, M. Schick, Xiao-jun Li   +4 more
core   +2 more sources

StarD7 Protein Deficiency Adversely Affects the Phosphatidylcholine Composition, Respiratory Activity, and Cristae Structure of Mitochondria [PDF]

, 2016
Yasuhiro Horibata, Hiromi Ando, Peixiang Zhang, Laurent Vergnes, Chieko Aoyama, Masahiko Itoh, Karen Reue, Hiroyuki Sugimoto   +7 more
openalex   +1 more source

A Cost‐Effective Hybrid Method For Homogeneous Matrix Coating in Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Using Simultaneous Spin and Spray Deposition

Analysis &Sensing, EarlyView.
This study introduces an in‐house spin coater for matrix‐assisted laser desorption/ionization mass spectrometry imaging, providing homogeneous matrix deposition via simultaneous spray and spin. The approach yields reproducible signals and clear metabolite distributions in complex tissues.
Lanaia Ítala Louzeiro Maciel, Jussara Valente Roque, Almir Custodio Batista Junior, Gabriel Henry Morais Dufrayer, Naará da Silva Balbino, Keilah Valéria Naves Cavalcante, Marcos Divino Ferreira Junior, Andrea Rodrigues Chaves, Boniek Gontijo Vaz   +8 more
wiley   +1 more source