Results 111 to 120 of about 84,430 (261)

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Immune cell-mediated effects of plasma lipids on heart failure: A two-step, two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Liu Z, Kwaku E, Cui Y, Xiong L, Li S, Zeng L, Du L, Wang K, Zheng J, Luo D, Zeng G, Yue R.   +11 more
europepmc   +1 more source

Gene turnover in the common ancestor of all C4 grasses

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira, Ahmed S. Alenazi, Sahr Mian, Ilia J. Leitch, Pascal‐Antoine Christin, Colin P. Osborne, Luke T. Dunning   +6 more
wiley   +1 more source

The efficacy and safety of acupuncture compared to Western medicine in patients with nonalcoholic fatty liver disease: A systematic review and meta‐analysis

Precision Medical Sciences, EarlyView.
This study conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs) to investigate whether acupuncture treatment is more beneficial than Western medicine treatment for patients with nonalcoholic fatty liver disease. The results showed that acupuncture was significantly superior to Western medicine in terms of clinical ...
Bin Yu, Yuxin Zhu, Yue Tong, Haomeng Zhang, Xiuli Lu, Hui He, Shuang Liang, Fuyu Xue, Haipeng Huang   +8 more
wiley   +1 more source

A new phase in phosphatidylcholines

Biophysical Journal, 1996
O'Leary, T.J., Mason, J.T.
openaire   +2 more sources

Genetic Evidence for Immune Cell-Lipid Mediation Pathways Linked to Esophageal Cancer and Associated Throat/Chest Pain Phenotypes. [PDF]

J Pain Res
Peng H, Bai Y, Zhao S, Zhang Y, Wu S, Wang J, Yang J, Yao W.   +7 more
europepmc   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Lipid and Foam Cell Accumulation as Novel Pathological Features of Benign Prostatic Hyperplasia

The Prostate, EarlyView.
ABSTRACT Background Benign prostatic hyperplasia (BPH) encompasses a heterogeneous set of pathological processes that instigate lower urinary tract symptoms (LUTS). Using a mouse model of steroid hormone imbalance–induced lower urinary tract dysfunction, we identified luminal lipid‐laden foamy macrophages, although their presence and contribution to ...
Dita Julianingsih, Samara V. Silver, Thaissa Horne, Kasun Gunawardena, Savannah Ward, Alicia Malewska, Douglas Strand, Julius Nyalwidhe, Ilya Sobol, Petra Popovics   +9 more
wiley   +1 more source

Critique of a Radically New Model for Plasma Membrane Bilayer Organization. [PDF]

Bioessays
Lange Y, Steck TL.
europepmc   +1 more source

x‐Ray Structure of Streptomyces avermitilis Phospholipase D Reveals a Ca2+‐Stabilized Expanded Active‐Site Cleft Adapted for Phospholipid Binding

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Phospholipase D (PLD) catalyzes the hydrolysis of phospholipids to generate phosphatidic acid and free head groups such as choline. Among bacterial PLD enzymes, Streptomyces chromofuscus PLD (SchPLD), a member of the alkaline phosphatase D (PhoD) superfamily, exhibits unique Ca2+‐dependent phospholipase activity.
Yoshiaki Yasutake, Tatsuya Hirata, Shunsuke Nomura, Kenji Konishi, Kazunari Yoneda, Shin‐ichi Sakasegawa, Haruhiko Sakuraba   +6 more
wiley   +1 more source