Results 191 to 200 of about 82,361 (247)

Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study

NMR in Biomedicine, Volume 39, Issue 4, April 2026.
Combined metabolomic analysis of the intracellular and extracellular portions of SH‐SY5Y cells revealed that, in the presence of Aβ 1–42, nicotine primarily influences pathways related to neurotransmission, energy metabolism, as well as the biosynthesis and degradation of membrane phospholipids.
Enza Napolitano, Carmen Marino, Manuela Grimaldi, Michela Buonocore, Angelo Santoro, Anna Maria D'Ursi   +5 more
wiley   +1 more source

Phospholipid composition in small airway lining fluid among tunnel construction workers exposed to respirable crystalline silica. [PDF]

Lipids Health Dis
Leite M, Larsson P, Kokelj S, Nordby KC, Alfonso JH, Koca H, Ulvestad B, Ellingsen DG, Olin AC.   +8 more
europepmc   +1 more source

Laurdan: Clarifying Photophysics and Advancing the Characterization of Extracellular Vesicles

ChemPhysChem, Volume 27, Issue 5, 13 March 2026.
Biophysical properties of extracellular vesicles (EVs) reflect their composition and membrane organization. We introduce a novel approach using time‐resolved emission spectra (TRES) phasor analysis of the polarity‐sensitive probe Laurdan to characterize membranes with complex compositions.
Petra Riegerová, Mariana Amaro, Peter Kapusta, Antonín Vlček, Martin Smolko, Karel Souček, Vendula Pospíchalová, Martin Hof, Šárka Pokorná   +8 more
wiley   +1 more source

Common genetic polymorphisms define one-carbon metabolite responses to different forms of choline in healthy adult males. [PDF]

Front Nutr
Butt N, Dong J, Shelp GV, Poole EM, Keathley JR, Bakovic M, Cho CE.   +6 more
europepmc   +1 more source

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

Advanced Science, Volume 13, Issue 14, 9 March 2026.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao, Yanbin Li, Shengqi Zhang, Yilin He, Zhiqi Liu, Juan Wang, Jingmin Hua, Jinyu Chen, Junru Zhong, Huan Zhong, Yiji Xia, Yong Cui, Liwen Jiang   +12 more
wiley   +1 more source

The Lipidome of the Lateral Ventricle Choroid Plexus Exhibits Sex-Specific Changes Across Aging. [PDF]

J Neurochem
Loupiac G, Andriambelo B, Avila-Lopez J, Vachon A, Avino M, Ahumada JR, Miard S, Picard F, Qiu Y, Kurland IJ, Laurent B, Plourde M.   +11 more
europepmc   +1 more source

Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution

Advanced Science, Volume 13, Issue 14, 9 March 2026.
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su, Huimin Pan, Yaqiang Liu, Wei Wang, Yang Jiao, Yumo Hang, Xiahe Huang, Yong E. Zhang, Yuhang Chen, Mei Ding, Xun Huang   +10 more
wiley   +1 more source

Integrative Mendelian randomization and spatial transcriptomics analysis reveals causal links between plasma lipidome and non-small cell lung cancer. [PDF]

Discov Oncol
Zhang B, Liu J, Guo Q, Wang H, Miao L, Zhou L.   +5 more
europepmc   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, Volume 13, Issue 14, 9 March 2026.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source