Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang +5 more
wiley +1 more source
Higher levels of plasma phosphatidylcholine (17:0_18:1) raise the risk of developing Parkinson's disease. [PDF]
Su D +8 more
europepmc +1 more source
Integrative Mendelian randomization and spatial transcriptomics analysis reveals causal links between plasma lipidome and non-small cell lung cancer. [PDF]
Zhang B +5 more
europepmc +1 more source
Animal cells dependent on exogenous phosphatidylcholine for membrane biogenesis.
Jeffrey D. Esko +2 more
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Abstract Background Lycium barbarum polysaccharide (LBP) has long been recognized as having a wide range of beneficial properties for improving proliferation. However, the protective effects and specific mechanisms of d‐galactose‐induced testicular dysfunction in reproductively senescent rats are not fully understood.
Wenxin Ma +8 more
wiley +1 more source
Genomic Insights into Lipid Dependency in Atypical Strains of Malassezia pachydermatis. [PDF]
Díaz L +4 more
europepmc +1 more source
Orthogonal <i>in vivo</i> and <i>in vitro</i> membrane engineering enables human-like lipid remodeling of bacterial magnetosomes for functional TrkA display. [PDF]
Tomoe R +5 more
europepmc +1 more source
Increases in sphingomyelin in response to TDP‐43 pathology in the disease‐affected motor cortex of amyotrophic lateral sclerosis (ALS) brain. Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by the degeneration of motor neurons and the presence of TAR DNA‐binding protein 43 (TDP‐43 ...
Finula I. Isik +4 more
wiley +1 more source
Identification of Plasma Biomarkers in Untreated Schizophrenia Patients Using Untargeted Lipid Metabolomics. [PDF]
Wang Z +4 more
europepmc +1 more source

