Enhancing Lipidomics With High‐Resolution Ion Mobility‐Mass Spectrometry
ABSTRACT Lipids, indispensable yet structurally intricate biomolecules, serve as critical regulators of cellular function and disease progression. Conventional lipidomics, constrained by limited resolution for isomeric and low‐abundance species, has been transformed by ion mobility‐mass spectrometry (IM‐MS).
Gaoyuan Lu +3 more
wiley +1 more source
Expression of cell-surface activation markers on human CD15<sup>+</sup> cells after selected non esterified fatty acid supplementations. [PDF]
Hunt AN +5 more
europepmc +1 more source
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler +7 more
wiley +1 more source
Association of <i>LPCAT1</i>*rs9728 Variant with Reduced Susceptibility to Neonatal Respiratory Distress Syndrome. [PDF]
Dorgham S +5 more
europepmc +1 more source
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
Exploring the genetic causal inference between plasma lipidome and lung carcinoma: a bidirectional mendelian randomization study. [PDF]
Pan H, Hu J, Gong S, Fei Y.
europepmc +1 more source
Interaction of Phosphatidylcholine with β-lactoglobulind
Eleanor M. Brown +3 more
openaire +3 more sources
Herein, a liver‐targeted nanohybrid formulation, SGLC/DOX@AG, is developed to enhance doxorubicin delivery and reduce vascular toxicity in hepatocellular carcinoma (HCC) treatment. Incorporating an albumin–glucosamine lipid complex, the system shows potent anticancer effects and minimized side effects across in vitro, in vivo, and cancer‐on‐a‐chip ...
Hyelim Kim +11 more
wiley +1 more source
Mini-review: Processed red meat intake and risk of neurodegenerative diseases. [PDF]
Chen KQ, Cao WJ, Liu Z, Liu RZ.
europepmc +1 more source
The membrane of intact human erythrocytes tolerates only limited changes in the fatty acid composition of its phosphatidylcholine [PDF]
Frans A. Kuypers +3 more
openalex +1 more source

