Results 241 to 250 of about 149,942 (303)
Regulated Cell Death in Idiopathic Pulmonary Fibrosis
The FASEB Journal, Volume 40, Issue 9, 15 May 2026.This graphical abstract illustrates regulated cell death (RCD) across key pulmonary cell types—including alveolar epithelial cells, fibroblasts, macrophages, and endothelial cells—modulated through a dynamic death modulation network within the IPF microenvironment.
Xiaoyue Pan +10 more
wiley +1 more source
Mendelian randomization analysis unveils causal associations between immune cells, metabolites, and lung cancer risk. [PDF]
Discov OncolMao Y, Fu T, Wang Y, Wang L.
europepmc +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source
Deep structural lipidomic profiling reveals C=C positional isomers as potential biomarkers in lung adenocarcinoma tissue. [PDF]
Transl Lung Cancer ResGu Y, Shao MM, Cui SP, Hu B, Li X.
europepmc +1 more source
Clinical Cardiology, Volume 49, Issue 5, May 2026.Apolipoprotein A‐I (ApoA‐I), the principal protein of HDL, plays a key role in reverse cholesterol transport, inflammation modulation, and plaque stabilization in atherosclerotic cardiovascular disease. Emerging ApoA‐I–based therapies, including CSL112, enhance cholesterol efflux capacity, though definitive reductions in cardiovascular events remain ...
Awais Habib +6 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.Multiomics analysis of the faecal samples from CRC patients found that upregulation of P. micra and PLA was associated with the CRC development. PLA from P. micra via pdhD genes could induce DNA damage via AHR signalling pathway to mediate carcinogenesis.
Shuang Guo +15 more
wiley +1 more source
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.This review synthesises current knowledge on gut microbiome involvement in obesity and hypertension, evaluates microbiome‐based therapeutic strategies, and identifies critical research gaps to guide future investigations aimed at mitigating the dual pandemics.
Andrej Belančić +7 more
wiley +1 more source
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Cy5-Labeled Phosphatidylcholine
Russian Journal of Bioorganic Chemistry, 2021Fluorescent lipid probes are widely used as tools for studying the properties of biological membranes and for studies of such biological functions of lipids as metabolic pathways and the molecular nature of diseases. In this report, we propose the new Cy5-labeled phosphatidylcholine (Cy5-PC) fluorescent lipid probe and describe its geometrical ...
I. A. Gracheva +6 more
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Phosphatidylcholine and cell death
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002Phosphatidylcholine (PC) constitutes a major portion of cellular phospholipids and displays unique molecular species in different cell types and tissues. Inhibition of the CDP-choline pathway in most mammalian cells or overexpression of the hepatic phosphatidylethanolamine methylation pathway in hepatocytes leads to perturbation of PC homeostasis ...
Cui, Z., Houweling, M.
openaire +3 more sources