Results 231 to 240 of about 155,795 (339)

Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms

open access: yesSmall Science, EarlyView.
This review highlights recent advances in engineering extracellular vesicles (EVs) as next‐generation cancer vaccines. It outlines their biological roles and antigen‐presenting capacity, explores key strategies for antigen loading and delivery optimization, and summarizes preclinical and clinical applications using EVs from diverse immune and tumor ...
Wonkyung Ahn   +4 more
wiley   +1 more source

Dual‐Targeted Glucose‐Dependent Insulinotropic Polypeptide‐Loaded Photothermal Nanoparticles to Prevent Obesity via Lipolysis and Browning of White Adipose Tissue

open access: yesSmall Science, EarlyView.
Current weight‐loss medications inevitably cause adverse effects such as depression or muscle loss. The developed GIP/ICG@P/R8 NPs specifically promoted energy expenditure by inducing browning, lipolysis and apoptosis of WAT in vitro and in vivo. The results showed a 9.23% weight reduction after 14 days, enhanced insulin sensitivity, improved fatty ...
Ting Xie   +11 more
wiley   +1 more source

Role of Phospholipids on Drug Dissolution in Polymer Solid Dispersions Prepared by Hot-Melt Extrusion. [PDF]

open access: yesACS Omega
de Carvalho DM   +7 more
europepmc   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

open access: yesSmall Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz   +5 more
wiley   +1 more source

Lipidome of high-density lipoprotein is strongly perturbed in hyperalphalipoproteinemia resulting from a rare mutation in endothelial lipase. [PDF]

open access: yesAtheroscler Plus
Pisciotta L   +8 more
europepmc   +1 more source

Path Dependence of Adsorption Behavior of Mixtures Containing Dipalmitoyl Phosphatidylcholine [PDF]

open access: bronze, 1982
Robert H. Notter   +3 more
openalex   +1 more source

Investigating Impacts of Amino Acids on the Structural Stability of Anionic Biomembranes

open access: yesChemSystemsChem, Volume 7, Issue 2, March 2025.
Glycine and lysine interact with the anionic membrane composed of POPC and POPG (1 : 1). Lysine partitions into the membrane and induces structural alterations, while the membrane remains impermeable to it. In contrast, glycine causes no physicochemical damage and permeates through the membrane.
Arslan Siddique   +6 more
wiley   +1 more source

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