Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms
This review highlights recent advances in engineering extracellular vesicles (EVs) as next‐generation cancer vaccines. It outlines their biological roles and antigen‐presenting capacity, explores key strategies for antigen loading and delivery optimization, and summarizes preclinical and clinical applications using EVs from diverse immune and tumor ...
Wonkyung Ahn +4 more
wiley +1 more source
The effect of Zuogui-Jiangtang-Yishen decoction on the intestinal flora's response to L-α-phosphatidylcholine and L-tyrosine in patients with diabetic kidney disease: an <i>in vitro</i> study. [PDF]
Yin Y +6 more
europepmc +1 more source
Immiscibility in phosphatidylcholine‐cholesterol mixtures [PDF]
openaire +3 more sources
Current weight‐loss medications inevitably cause adverse effects such as depression or muscle loss. The developed GIP/ICG@P/R8 NPs specifically promoted energy expenditure by inducing browning, lipolysis and apoptosis of WAT in vitro and in vivo. The results showed a 9.23% weight reduction after 14 days, enhanced insulin sensitivity, improved fatty ...
Ting Xie +11 more
wiley +1 more source
Role of Phospholipids on Drug Dissolution in Polymer Solid Dispersions Prepared by Hot-Melt Extrusion. [PDF]
de Carvalho DM +7 more
europepmc +1 more source
A Simple Biosynthetic Method for Preparation of High Specific Radioactivity Phosphatidylcholine
Michihiro Sugano, Munehiko Yamamoto
openalex +2 more sources
Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz +5 more
wiley +1 more source
Lipidome of high-density lipoprotein is strongly perturbed in hyperalphalipoproteinemia resulting from a rare mutation in endothelial lipase. [PDF]
Pisciotta L +8 more
europepmc +1 more source
Path Dependence of Adsorption Behavior of Mixtures Containing Dipalmitoyl Phosphatidylcholine [PDF]
Robert H. Notter +3 more
openalex +1 more source
Investigating Impacts of Amino Acids on the Structural Stability of Anionic Biomembranes
Glycine and lysine interact with the anionic membrane composed of POPC and POPG (1 : 1). Lysine partitions into the membrane and induces structural alterations, while the membrane remains impermeable to it. In contrast, glycine causes no physicochemical damage and permeates through the membrane.
Arslan Siddique +6 more
wiley +1 more source

