Serum albumin enhances the uptake of [3H]cholesterol from phosphatidylcholine vesicles by cultured human fibroblasts [PDF]
J. Peter Slotte, S. Björkerud
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Immiscibility in phosphatidylcholine‐cholesterol mixtures [PDF]
openaire +3 more sources
This study presents a novel method for rapidly evaluating dermal drug delivery systems (DDSs). Using mass spectrometry imaging and automated data analysis, it visualizes drug distribution within skin layers in under 10 min. Tested with three nanoscale DDSs for antifungal terbinafine, the approach reveals key differences in drug permeation depth and ...
Ravit Yakobi Arancibia+9 more
wiley +1 more source
Lipidomics-based investigation of its impact on the pathogenesis of coronary atherosclerosis: a Mendelian randomization study. [PDF]
Wang Q, Cao Y, Jia L.
europepmc +1 more source
A Simple Biosynthetic Method for Preparation of High Specific Radioactivity Phosphatidylcholine
Michihiro Sugano, Munehiko Yamamoto
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Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz+5 more
wiley +1 more source
Association of the lipidome with type 1 diabetes and the mediated effect of metabolites: A Mendelian randomization study. [PDF]
Yin Y+7 more
europepmc +1 more source
Investigating Impacts of Amino Acids on the Structural Stability of Anionic Biomembranes
Glycine and lysine interact with the anionic membrane composed of POPC and POPG (1 : 1). Lysine partitions into the membrane and induces structural alterations, while the membrane remains impermeable to it. In contrast, glycine causes no physicochemical damage and permeates through the membrane.
Arslan Siddique+6 more
wiley +1 more source
Changes in plasma lipid composition upon glucocorticoid treatment in patients with primary immune thrombocytopenia. [PDF]
Ji L+10 more
europepmc +1 more source
Plasmalogens are specialized lipids affecting the membrane structure, dynamics, and key cell signaling pathways. They protect cells from oxidative damage. Plasmalogen deficiency is associated with severe diseases. Lipid nanoparticles and nanomedicine offer unexplored therapeutic potential for restoring plasmalogen levels under pathological conditions ...
Yu Wu+3 more
wiley +1 more source