Results 251 to 260 of about 149,516 (340)

Multiomics: Two-Sample, Bidirectional, Multivariate and Mediated Mendelian Randomization Analysis of Allergic Rhinitis. [PDF]

Indian J Otolaryngol Head Neck Surg
Zhong C, Wang LH, Zhang HP, Ji L, Guo Y.
europepmc   +1 more source

Phosphatidylethanol in post‐mortem blood: A comparative study of blood matrices and its stability at routine storage conditions

Journal of Forensic Sciences, EarlyView.
Abstract Determination of alcohol markers in post‐mortem cases can be useful to classify drinking habits and potential alcohol habituation prior to death. Phosphatidylethanol (PEth) is a direct alcohol marker and is already commonly used in a variety of contexts.
Jeremai Hose, Hilke Andresen‐Streichert, Mario Thevis, Markus A. Rothschild, Martin Juebner   +4 more
wiley   +1 more source

Lipidomics Reveals Common Mechanisms in Polycystic Ovarian Syndrome, Recurrent Spontaneous Abortion, and Infertility: A Genetic-Based Analysis. [PDF]

Int J Womens Health
Tao A, Wu T, Han X, Niu D, Feng X.
europepmc   +1 more source

Short‐Term Severe Energy Restriction Promotes Molecular Health and Reverses Aging Signatures in Adults With Prediabetes in the PREVIEW Study

Aging Cell, EarlyView.
Severe short‐term energy restriction in adults with prediabetes led to a significant reduction in circulating proteins linked to inflammation, senescence, and protein turnover. These changes, partly mediated by extracellular vesicles, suggest systemic dietary‐induced benefits beyond glycemic control, including improved aging biomarkers.
Maria Lastra Cagigas, Andrius Masedunskas, Yao Lin, Samantha J. Emery‐Corbin, Jumana M. Yousef, Laura F. Dagley, Sam Olechnowicz, Rory Bowden, Rachael Hayward, Gary Low, Roslyn Muirhead, Jennie Brand‐Miller, Mikael Fogeltholm, Anne Raben, Marco Demaria, Stephen J. Fuller, Luigi Fontana   +16 more
wiley   +1 more source

Clinical, genetic and functional perspectives on ATP-binding cassette subfamily B member 4 variants in five cholestasis adults. [PDF]

World J Gastroenterol
Weng YH, Zheng YF, Yin DD, Xiong QF, Li JL, Li SX, Chen W, Yang YF.   +7 more
europepmc   +1 more source

Cross‐sectional and longitudinal metabolomics‐based profiles associated with oral contraceptive and progestin‐only pill use: A Finnish population‐based study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In a metabolomics study of over 200 metabolites in 1721 fertile‐aged women, we found that current use of combined oral contraceptives (COC), especially third‐generation and other COCs, is associated with altered levels of several metabolic measures compared to nonuse of hormonal contraception or to use of a levonorgestrel intrauterine device (LNG‐IUD).
Elena Toffol, Jari Haukka, Pekka Jousilahti, Lara Lehtoranta, Anni Joensuu, Timo Partonen, Iris Erlund, Oskari Heikinheimo   +7 more
wiley   +1 more source

M28 family peptidase derived from <i>Peribacillus frigoritolerans</i> initiates trained immunity to prevent MRSA via the complosome-phosphatidylcholine axis. [PDF]

Gut Microbes
Zhou CK, Liu ZZ, Peng ZR, Luo XY, Zhang XM, Zhang JG, Zhang L, Chen W, Yang YJ.   +8 more
europepmc   +1 more source

Predicting Surfactant Need at Birth: Failed Validation of a Bedside Method Using Gastric Aspirates

Acta Paediatrica, EarlyView.
ABSTRACT Aim To validate a prototype point‐of‐care (POC) test for the lecithin/sphingomyelin (L/S) ratio by identifying the optimal L/S cut‐off for predicting surfactant need in preterm infants < 30 weeks' gestation using gastric aspirates (GAS) sampled at birth and to assess clinical feasibility.
Christian Heiring, Porntiva Poorisrisak, Niklas Breindahl, Gitte Zachariassen, Maria‐Christina Eckardt, Anne‐Cathrine Viuff, Lars Bender, Peter Agergaard, Lise Aunsholt, Tine Brink Henriksen   +9 more
wiley   +1 more source

Effects of Dietary Phosphatidylcholine Supplementation on Growth Performance, Antioxidant Capacity, Fatty Acid Composition, and Lipid Metabolism of Juvenile Eriocheir sinensis-Fed Different Oil Sources. [PDF]

Aquac Nutr
Lin Z, Wang X, Bu X, Huang Q, Wang H, Li E, Qin J, Chen L.   +7 more
europepmc   +1 more source

Matrix metalloproteinase inhibition protects against junctophilin‐2 proteolysis during doxorubicin‐induced cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Treatment of cancer patients with anthracyclines is known to cause dose‐dependent cardiotoxicity through several mechanisms including enhanced oxidative stress, ultimately resulting in defective excitation–contraction coupling.
Wesam Bassiouni, Brandon Y. H. Chan, Andrej Roczkowsky, Joshua W. Kranrod, Zabed Mahmud, Joseph O. Primeau, Woo Jung Cho, Howard S. Young, John M. Seubert, Richard Schulz   +9 more
wiley   +1 more source