Results 321 to 330 of about 149,516 (340)
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Synthesis of a photocleavable bola-phosphatidylcholine
Bioorganic & Medicinal Chemistry, 2023Phosphatidylinositol transfer proteins (PITPs) are ubiquitous in eukaryotes and are involved in the regulation of phospholipid metabolism, membrane trafficking, and signal transduction. Sec14 is a yeast PITP that has been shown to transfer phosphatidylinositol (PI) or phosphatidylcholine (PC) from the endoplasmic reticulum to the Golgi.
Sean Wilson +6 more
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1981
The effect of dicarboxylic phosphatidylcholines (glutaryl phosphatidylcholine) on the stability and phase transition of phosphatidylcholine liposomes is examined by using liposomes prepared with egg phosphatidylcholine or dipalmitoyl phosphatidylcholine and by varying the surface charge by addition of dicetyl phosphate.
Louis Douste-Blazy +2 more
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The effect of dicarboxylic phosphatidylcholines (glutaryl phosphatidylcholine) on the stability and phase transition of phosphatidylcholine liposomes is examined by using liposomes prepared with egg phosphatidylcholine or dipalmitoyl phosphatidylcholine and by varying the surface charge by addition of dicetyl phosphate.
Louis Douste-Blazy +2 more
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The interaction of ions with phosphatidylcholine bilayers
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1977Abstract The interaction of lanthanides and other cations with phosphatidylcholine bilayers present as single bilayer vesicles in 2H2O has been investigated in terms of stoichiometry, apparent binding constants and environmental conditions. Lanthanides are shown to form 2 : 1 (molar ratio) phosphatidylcholine to metal ion complexes.
R. J. P. Williams +5 more
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1980
Freeze-fracture electron microscopy is used to study the rippled texture in pure dimyristoyl and dipalmitoyl phosphatidylcholine membranes and in mixtures of dimyristoyl phosphatidylcholine and cholesterol. Evidence is presented that the apparent phase transition properties of multilamellar liposomes may be dependent on the manner in which liposomes ...
Bruce R. Copeland, Harden M. McConnel
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Freeze-fracture electron microscopy is used to study the rippled texture in pure dimyristoyl and dipalmitoyl phosphatidylcholine membranes and in mixtures of dimyristoyl phosphatidylcholine and cholesterol. Evidence is presented that the apparent phase transition properties of multilamellar liposomes may be dependent on the manner in which liposomes ...
Bruce R. Copeland, Harden M. McConnel
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Journal of the Physical Society of Japan, 1979
Phase diagram has been determined with X-rays for bilayer membranes of mixed lipids of dioleoyl-phosphatidylcholine/dipalmitoyl-phosphatidylcholine in water. Observed liquidus lines were reproduced well by calculation on the assumption of ideal mixing of the two lipids.
Kishio Furuya, Toshio Mitsui
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Phase diagram has been determined with X-rays for bilayer membranes of mixed lipids of dioleoyl-phosphatidylcholine/dipalmitoyl-phosphatidylcholine in water. Observed liquidus lines were reproduced well by calculation on the assumption of ideal mixing of the two lipids.
Kishio Furuya, Toshio Mitsui
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Proceedings, annual meeting, Electron Microscopy Society of America, 1991
There is great interest in the process of lipid self-assembly, especially the microstructure formed from lipid mixtures. Spontaneous unilamellar vesicles have been reported by Roberts from mixtures of long-chain lecithins and short-chain lecithins. Alone, dipalmitoyi phophatidylcholine (DPPC) forms normal multilamellar phases, a solid Lβ phase up to ...
E. Naranjo, J.A.N. Zasadzinski
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There is great interest in the process of lipid self-assembly, especially the microstructure formed from lipid mixtures. Spontaneous unilamellar vesicles have been reported by Roberts from mixtures of long-chain lecithins and short-chain lecithins. Alone, dipalmitoyi phophatidylcholine (DPPC) forms normal multilamellar phases, a solid Lβ phase up to ...
E. Naranjo, J.A.N. Zasadzinski
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Lack of efficacy of phosphatidylcholine in ataxias
Neurology, 1988We gave phosphatidylcholine orally at a daily dosage of 9 grams for 4 years to 20 subjects with Friedreich's ataxia (FA) and 24 with olivopontocerebellar atrophy (OPCA). There was no clinical improvement during the follow-up compared with 12 ataxic patients (six FA and six OPCA) who did not receive any treatment.
SORBI, SANDRO +5 more
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Interaction of fluoxetine with phosphatidylcholine liposomes
Biophysical Chemistry, 2005Fluoxetine (Prozac) is one of the latest of a new generation of antidepressants, approved by FDA in 2002. The interactions of fluoxetine with multilamellar liposomes of pure phosphatidylcholine (PC) or containing cholesterol 10% molar were studied as a function of the lipid chain lengths, using differential scanning calorimetry and spin labelling EPR ...
MOMO, Federico +2 more
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Chemistry and Physics of Lipids, 1976
The solubility of phosphatidylcholine (PC) was studied by the spectroscopic analysis and the measurement of the solubility. The qualitative analysis of infrared absorption spectra confirmed the existence of two types of hydrogen bondings between chloroform and PC, one between chloroform and the C=O group of PC and the other between chloroform and the ...
Tsunetake Fujiyama +2 more
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The solubility of phosphatidylcholine (PC) was studied by the spectroscopic analysis and the measurement of the solubility. The qualitative analysis of infrared absorption spectra confirmed the existence of two types of hydrogen bondings between chloroform and PC, one between chloroform and the C=O group of PC and the other between chloroform and the ...
Tsunetake Fujiyama +2 more
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Cystic fibrosis and phosphatidylcholine biosynthesis
Clinica Chimica Acta, 1994The cystic fibrosis (CF) gene defect may be associated with a defect in membrane recycling. We have investigated the metabolism of the main constituent of plasma membrane, phosphatidylcholine (PC). In this study of platelets and fibroblasts, we show an increased uptake of choline into PC of CF cells as compared with normal cells.
M. M. Ulane +5 more
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