Promising Prodiginins Biological Activities
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto+6 more
wiley +1 more source
AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
Methyl metabolites in the one-carbon cycle, such as phosphatidylcholines and S-adenosylmethionine, play a role in hepatic triglyceride regulation. Here Kim et al.
Young-Chae Kim+9 more
doaj +1 more source
DL- and PO-phosphatidylcholines as a promising learning and memory enhancer
In the water maze test, oral administration with 1,2-dilynoleoyl-sn-glycero-3-phosphocholine (DLPhtCho)(5 mg/kg) alone or DLPhtCho (5 mg/kg) plus 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPhtCho)(5 mg/kg) significantly shortened the prolonged ...
Nishizaki Tomoyuki+2 more
doaj +1 more source
Presence of a Spatially Varying Electric Field at Lipid-Water Interface with Na/K ratio in Water [PDF]
The ion-lipid interface in Langmuir monolayers of Dipalmitoylphosphatidylcholine (DPPC) on pure water and 10 mM solutions of Na+ and K+ at different [K+]/[Na+] (a), atom/atom ratios, were studied initially by Surface Pressure (p) versus Specific Molecular Area (A) isotherms.
arxiv
Action of pancreatic phospholipase A2 on phosphatidylcholine bilayers in different physical states [PDF]
Jos A.F. Op den Kamp+2 more
openalex +1 more source
SAAP‐148 Oligomerizes into a Hexamer Forming a Hydrophobic Inner Core
The highly cationic and hydrophobic antimicrobial peptide SAP‐148 effectively eradicates multidrug‐resistant bacteria, persistent cells, and biofilms without inducing resistance. Its efficiency is likely due to its ability to disrupt bacterial membranes as an oligomer, forming a stable alpha‐helical hexameric bundle with three parallel dimers that ...
Aden Hodzic+15 more
wiley +1 more source
Use of 31PNMR spectroscopy to follow the time course of phosphatidylcholine chemical synthesis.
31PNMR spectroscopy is shown to be useful for studying the chemical synthesis of phosphatidylcholine from phosphatidic acid and choline. Sharp, well-resolved resonances were obtained by chelating multivalent cations, thereby enabling quantitation of ...
P R Meers, G W Feigenson
doaj
Recent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid
This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Concetta Avitabile+4 more
wiley +1 more source
There is a phenotype of obese individuals termed metabolically healthy obese that present a reduced cardiometabolic risk. This phenotype offers a valuable model for investigating the mechanisms connecting obesity and metabolic alterations such as Type 2 ...
Laia Bertran+5 more
doaj +1 more source
Rate-limiting steps in the cytidine pathway for the synthesis of phosphatidylcholine and phosphatidylethanolamine [PDF]
Juan P. Infante
openalex +1 more source