Results 181 to 190 of about 31,592 (359)

Targeting SHMT2‐mediated membrane phospholipid remodeling for enhanced anti‐GCSCs treatment

open access: yesInterdisciplinary Medicine, EarlyView.
Depletion of serine via serine hydroxymethyltransferase‐2 (SHMT2) knockdown in gastric cancer (GC) disrupted the maintenance of gastric cancer stem cell stemness by inducing membrane phospholipid remodeling and aberrant CD44 shedding within membrane lipid rafts. The synthesized HA‐Exo‐si SHMT2 demonstrated enhanced therapeutic efficacy and safety in GC.
Liping Yang   +10 more
wiley   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang   +12 more
wiley   +1 more source

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

open access: yesInterdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao   +6 more
wiley   +1 more source

Mixed Monolayers Containing Phosphatidylcholine, Cholesterol, Oleic Acid, and Mono- and Triolein. [PDF]

open access: bronze, 1979
Bo Lundberg   +7 more
openalex   +1 more source

Value of Magnetic Resonance Spectroscopy for Examining Fetal Brain Development in Mid‐ to Late Pregnancy

open access: yesiRADIOLOGY, EarlyView.
This study demonstrates that the ratio of tNAA to tCr increases during gestation, which correlates with an increase in the number of neurons and cellular energy metabolism in the fetal brain as gestational weeks progress. Additionally, tCho levels exhibit a progressive decrease with advancing gestational weeks, indicating the ongoing development of the
Dejuan Shan   +5 more
wiley   +1 more source

Pressure-dependent adhesion between solid-supported PC-lipid bilayers and vesicles under electric fields [PDF]

open access: yesarXiv
Fusion of lipid bilayers in membranes is important in processes from vesicle-cell interactions (as in drug delivery) to exosome-cell signaling, while transient transmembrane electric fields are known to occur spontaneously. Two contacting phosphatidylcholine (PC) lipid membranes are known to fuse into one under external electric fields, suggesting that
arxiv  

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