Results 171 to 180 of about 80,395 (343)

Specific Lipidomic Shifts in Chronic Lymphocytic Leukemia at Diagnosis. [PDF]

Cancers (Basel)
Wojnicka J, Kiełbus M, Mertowska P, Mertowski S, Grywalska E, Sosnowski P, Wielgosz A, Kozub-Pędrak A, Sosnowska-Pasiarska B, Klatka M, Klatka J, Błażewicz A.   +11 more
europepmc   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Multi-Omics Reveals Mechanisms of Metabolic Rejuvenation in Aged Mice and Pre-Frail Older Men by Losartan. [PDF]

Aging Cell
Bene MR, Zhang C, Westbrook R, Gabrawy M, Marx R, Wu Y, Khadeer M, Ubaida-Mohien C, Ferrucci L, Moaddel R, Le A, Walston JD, Lee JL, Abadir PM.   +13 more
europepmc   +1 more source

Nutritional genomics and metabolomics in obesity and type 2 diabetes [PDF]

, 2014
Hu, Frank B, Narasimhan, Kothandaraman
core   +1 more source

x‐Ray Structure of Streptomyces avermitilis Phospholipase D Reveals a Ca2+‐Stabilized Expanded Active‐Site Cleft Adapted for Phospholipid Binding

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Phospholipase D (PLD) catalyzes the hydrolysis of phospholipids to generate phosphatidic acid and free head groups such as choline. Among bacterial PLD enzymes, Streptomyces chromofuscus PLD (SchPLD), a member of the alkaline phosphatase D (PhoD) superfamily, exhibits unique Ca2+‐dependent phospholipase activity.
Yoshiaki Yasutake, Tatsuya Hirata, Shunsuke Nomura, Kenji Konishi, Kazunari Yoneda, Shin‐ichi Sakasegawa, Haruhiko Sakuraba   +6 more
wiley   +1 more source

Comprehensive first-trimester targeted metabolomics for early prediction and understanding of GDM pathophysiology. [PDF]

Front Mol Biosci
Mojsak P, Godlewski A, Sołowiej K, Kulczynska-Przybik A, Chmielewska S, Mroczko B, Szelachowska M, Krętowski A, Ciborowski M.   +8 more
europepmc   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

The endothelial plasma membrane lipidome and its remodeling under hyperglycemia: an exploratory study. [PDF]

Front Mol Biosci
Reis A, Sohrabi Y, Diaz-Sanchez L, Dias Araújo AR, Leffers M, Antonny B, Rudnitskaya A, Vitorino R, Dias IHK.   +8 more
europepmc   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Editorial: Advances in neurodevelopmental and neurodegenerative disease research: focus on innovative human-relevant brain research. [PDF]

Front Neurosci
Roe KV, Grassi S, Chiola S, Miller RJ.
europepmc   +1 more source