Results 271 to 280 of about 31,592 (359)

Early Prediction of Fetal Macrosomia Through Maternal Lipid Profiles. [PDF]

Int J Mol Sci
Chagovets V, Frankevich N, Starodubtseva N, Tokareva A, Derbentseva E, Yuryev S, Kutzenko A, Sukhikh G, Frankevich V.   +8 more
europepmc   +1 more source

Mefloquine Suppresses Metastasis in Renal Cell Carcinoma Through Targeting SPC25

Cancer Science, Volume 116, Issue 5, Page 1239-1254, May 2025.
We addressed the clinical issue of renal cell carcinoma metastasis by identifying SPC25 protein as a research target through bioinformatics techniques and validation with clinical samples. We comprehensively validated the function of SPC25 protein and determined its impact on renal cancer.
Yongbo Wang, He Wang, Yipeng Xu, Jiawei Ling, Chuhong Zong, Yan Zhang, Xiaoxuan Guo, Guanan Zhao, Yuan Zhou, Jiahui Zhao, Pengrong Lou, Xigao Liu, Tengfei Xu, Qi Ma   +13 more
wiley   +1 more source

Identifying Metabolomic Mediators of the Physical Activity and Colorectal Cancer Relationship. [PDF]

Cancer Epidemiol Biomarkers Prev
Papadimitriou N, Kazmi N, Tsilidis KK, Richmond RC, Lynch BM, Bendinelli B, Ricceri F, Sánchez MJ, Trobajo-Sanmartín C, Jakszyn P, Simeon V, Severi G, Perduca V, Truong T, Ferrari P, Keski-Rahkonen P, Weiderpass E, Eichelmann F, Schulze MB, Katzke V, Fortner RT, Heath AK, Aune D, Harewood R, Dahm CC, Llorente A, Gunter MJ, Murphy N, Lewis SJ.   +28 more
europepmc   +1 more source

Terpene Hydroperoxides as Lipid Peroxidation Inducers: Biomimetic and HaCaT Cell Studies in Allergic Contact Dermatitis

Contact Dermatitis, EarlyView.
Fragrance terpene hydroperoxides from limonene, linalool, and geraniol induced the formation of lipid peroxidation products when incubated with PLPC liposomes or in vitro with HaCaT keratinocytes. Lipid peroxidation products included aldehydes, ketones, and hydroperoxides.
Aaron I. Moore, Ana S. P. Moreira, Tiago Conde, Tânia Melo, Pedro Domingues, Niamh M. O'Boyle, M. Rosário Domingues   +6 more
wiley   +1 more source

GPD1L‐Mediated Glycerophospholipid Metabolism Dysfunction in Women With Diminished Ovarian Reserve: Insights From Pseudotargeted Metabolomic Analysis of Follicular Fluid

Cell Proliferation, EarlyView.
Our study demonstrated the downregulation of GPD1L and its mediated glycerophospholipid metabolism dysfunction in patients with diminished ovarian reserve. Moreover, we verified that GPD1L knockdown leads to increased cell apoptosis and mitochondrial dysfunction of KGN cells, as well as impaired oocyte quality.
Jiaqi Wu, Xuehan Zhao, Ying Fang, Cong Wang, Yichang Tian, Wan Tu, Qiqian Wu, Long Yan, Xiaokui Yang   +8 more
wiley   +1 more source

Evaluating Metabolic Profiling of Human Milk Using Biocrates MxP^® QUANT 500 Assay. [PDF]

Metabolites
Hampel D, Shahab-Ferdows S, Kac G, Allen LH.   +3 more
europepmc   +1 more source

Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells

Cell Proliferation, EarlyView.
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai, Jialei Hua, Donghua Meng, Yue Xu, Benfu Zhong, Miao Liu, Zhaosong Wang, Wei Zhou, Liming Liu, Hailong Wang, Yang Liu, Lifang Li, Xiuju Chen, Yueguo Li   +13 more
wiley   +1 more source

Exploring lipidome mediated inflammatory pathways in acute pancreatitis using mendelian randomization. [PDF]

Sci Rep
Liu W, Yang S, Li Y, Tenzing D, Shi R, Jiang Y, Deng H, Mao E, Chen Y, Wang Y.   +9 more
europepmc   +1 more source

The evolving role of positron emission tomography in precision prostate cancer biopsy

European Journal of Clinical Investigation, EarlyView.
Prostate biopsy plays a pivotal role in the detection and characterization of prostate cancer. PSMA PET‐targeted biopsy represents a significant advancement in prostate cancer diagnostics, offering higher sensitivity, specificity and accuracy in detecting clinically significant lesions compared to traditional methods. PSMA PET, when combined with mpMRI,
Alessio Imperiale, Valentina Berti, Roberto Luigi Cazzato, Darejan Mamulashvili Bessac, Alice Ressault, Luca Vaggelli, Mehdi Helali, Camilo Garcia, Hervé Lang, Desirée Deandreis, Luc Mertz, Afshin Gangi   +11 more
wiley   +1 more source

Metabolomics in juvenile idiopathic arthritis: A distinct profile in patients under methotrexate. [PDF]

Clinics (Sao Paulo)
Tomioka RB, Ferreira GRV, Aikawa NE, Maciel GAR, Junior JMS, Baracat EC, Bonfá E, da Silva IDCG, da Silva CA.   +8 more
europepmc   +1 more source