Results 141 to 150 of about 82,133 (342)

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

The FEBS Journal, EarlyView.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva, Lena Sophie Fritsch, Leander Mika Koch, Anton Effing, Meriyem Aktas, Franz Narberhaus   +5 more
wiley   +1 more source

Enzymatic Characterization of Leishmania major Phosphatidylethanolamine Methyltransferases LmjPEM1 and LmjPEM2

, 2015
Phosphatidylcholine (PC) is the most abundant phospholipid in the membranes of the human parasite Leishmania. It is synthesized via two metabolic routes, the de novo pathway that starts with the uptake of choline, and the threefold methylation of ...
Dahlstrom, Kelly, Bibis, Stergios S., Zhu, Tongtong, Zufferey, Rachel   +3 more
core  

A deazaadenosine-insensitive methylation of phosphatidylethanolamine is involved in lipoprotein secretion

, 1986
We have examined the effect of inhibitors of methylation of phosphatidylethanolamine on lipoprotein secretion from cultured rat hepatocytes. The incorporation of [1-3H]ethanolamine into phosphatidylcholine of hepatocytes and secreted lipoproteins was ...
Vance, Jean E., Vance, Dennis E., Jean E. Vance, Dennis E. Vance   +3 more
core   +1 more source

Phosphatidylserine Decarboxylase Regulates Retinal Ganglion Cell Neurite Outgrowth with Altered Somal Membrane Fluidics and Mitochondrial Morphology

Biomolecules
Mitochondrial lipid metabolism is an emerging regulator of neuronal regeneration, yet its role remains poorly defined. We investigated the function of phosphatidylserine decarboxylase (PSD), a mitochondrial enzyme that converts phosphatidylserine to ...
Sean D. Meehan, Sofia Yarosh, Victoria Pereira, Isabella Moceri, Sanjoy K. Bhattacharya   +4 more
doaj   +1 more source

LC-MS/MS analysis of carboxymethylated and carboxyethylated phosphatidylethanolamines in human erythrocytes and blood plasma [PDF]

, 2010
Naoki Shoji, Kiyotaka Nakagawa, Akira Asai, Ikuko Fujita, Aya Hashiura, Yasushi Nakajima, Shinichi Oikawa, Teruo Miyazawa   +7 more
openalex   +1 more source

Symmetrically substituted dichlorophenes inhibit N -acyl-phosphatidylethanolamine phospholipase D [PDF]

, 2020
Geetika Aggarwal, Jonah E. Zarrow, Zahra Mashhadi, Charles R. Flynn, Paige N. Vinson, C. David Weaver, Sean S. Davies   +6 more
openalex   +1 more source

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

The FEBS Journal, EarlyView.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger, Alice Wiedmann, Rayan Hassan M. Elshikhidriss, Thomas Brunner   +3 more
wiley   +1 more source

Northern cod (Gadus morhua) movement: insights from acoustic telemetry and genomics

Journal of Fish Biology, EarlyView.
Abstract Knowledge of the timing and diversity of fish movements within a commercially exploited stock complex is required to ensure the sustainability of fisheries. Although migration can be driven by environmental factors, genomic mechanisms also play an important role in this complex life‐history trait. The northern cod (Gadus morhua) stock complex,
M. Lisette Delgado, Nicole Smith, Frederick Whoriskey, Steve Devitt, Emilie Novaczek, Corey J. Morris, Tony Kess, Ian Bradbury, Sara Iverson, Paul Bentzen, Daniel E. Ruzzante   +10 more
wiley   +1 more source

Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei.

, 2009
Phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are the two major constituents of eukaryotic cell membranes. In the protist Trypanosoma brucei, PE and PC are synthesized exclusively via the Kennedy pathway.
Michael K. Shaw, Gluenz, E, Schneider, A, Shaw, Michael, Gluenz, Eva, Keith Gull, André Schneider, Signorell, A, Rettig, Jochen, Shaw, MK, Aita Signorell, Gull, K, Eva Gluenz, Shaw, Michael K., Signorell, Aita, Bütikofer, Peter, Bütikofer, P, Jochen Rettig, Gull, Keith, Schneider, André, Rettig, J, Peter Bütikofer   +21 more
core   +1 more source

Targeted lipidomics between hPheo1 and SDHB KD cells reveal changes in bioactive lipids and PKC with polyamine pathway inhibition. [PDF]

Physiol Rep
Abstract Pheochromocytoma and paraganglioma with a succinate dehydrogenase B subunit (SDHB) pathogenic variant are associated with a significant chance for metastasis. Polyamine pathway inhibitor N1,N11‐diethylnorspermine (DENSPM) was previously shown to inhibit cell growth in progenitor cells derived from a human pheochromocytoma (hPheo1).
Alli AA, Bala N, Xu Y, Denslow ND, Ghayee HK.   +4 more
europepmc   +2 more sources