Results 1 to 10 of about 31,010 (310)

Giant Vesicles Produced with Phosphatidylcholines (PCs) and Phosphatidylethanolamines (PEs) by Water-in-Oil Inverted Emulsions

Life, 2021
(1) Background: giant vesicles (GVs) are widely employed as models for studying physicochemical properties of bio-membranes and artificial cell construction due to their similarities to natural cell membranes.
Boying Xu, Jinquan Ding, Jian Xu, Tetsuya Yomo   +3 more
doaj   +2 more sources

DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression

Redox Biology, 2017
Activated platelets generate an eicosanoid proposed to be 8-hydroxy-9,10-dioxolane A3 (DXA3). Herein, we demonstrate that significant amounts of DXA3 are rapidly attached to phosphatidylethanolamine (PE) forming four esterified eicosanoids, 16:0p, 18:0p,
Maceler Aldrovandi, Christine Hinz, Sarah N. Lauder, Helen Podmore, Martin Hornshaw, David A. Slatter, Victoria J. Tyrrell, Stephen R. Clark, Lawrence J. Marnett, Peter W. Collins, Robert C. Murphy, Valerie B. O’Donnell   +11 more
doaj   +2 more sources

Phosphatidylethanolamines link ferroptosis and autophagy during appressorium formation of rice blast fungus. [PDF]

Mol Plant Pathol
A cell death pathway, ferroptosis, occurs in conidial cells and is critical for formation and function of the infection structure, the appressorium, in the rice blast fungus Magnaporthe oryzae. In this study, we identified an orthologous lysophosphatidic
Liu Q, Long R, Lin C, Bi X, Liang Z, Deng YZ.   +5 more
europepmc   +2 more sources

Sex-Associated Metabolites and Incident Stroke, Incident Coronary Heart Disease, Hypertension, and Chronic Kidney Disease in the REGARDS Cohort. [PDF]

J Am Heart Assoc
Background Sex disparities exist in cardiometabolic diseases. Metabolomic profiling offers insight into disease mechanisms, as the metabolome is influenced by environmental and genetic factors. We identified metabolites associated with sex and determined
Couch CA, Ament Z, Patki A, Kijpaisalratana N, Bhave V, Jones AC, Armstrong ND, Cushman M, Kimberly WT, Irvin MR.   +9 more
europepmc   +2 more sources

LC-MS/MS analysis of carboxymethylated and carboxyethylated phosphatidylethanolamines in human erythrocytes and blood plasma[S]

Journal of Lipid Research, 2010
An amino group of phosphatidylethanolamine (PE) is considered as a target for nonenzymatic glycation, and the potential involvement of lipid glycation in the pathogenesis of diabetic complications has generated interest.
Naoki Shoji, Kiyotaka Nakagawa, Akira Asai, Ikuko Fujita, Aya Hashiura, Yasushi Nakajima, Shinichi Oikawa, Teruo Miyazawa   +7 more
doaj   +2 more sources

Investigating plasma lipid profiles in association with Parkinson's disease risk. [PDF]

NPJ Parkinsons Dis
Parkinson’s Disease (PD) is associated with lipid metabolic disturbances, but the specific roles of lipids in its pathogenesis are unclear. This Mendelian Randomization (MR) study utilized GWAS data and IVW methods to investigate plasma lipids and PD ...
Zhang H, Cao F, Yu J, Liang Y, Wu Y.
europepmc   +2 more sources

Lipidomic profiling of the cerebrospinal fluid in moyamoya angiopathy patients. [PDF]

Orphanet J Rare Dis
Background Moyamoya angiopathy (MA) is a rare cerebrovascular disorder which can occur in both children and young adults, characterized by progressive occlusion of the intracranial carotid arteries, leading patients to ischemic and haemorrhagic strokes ...
Potenza A, Gorla G, Carrozzini T, Pollaci G, Dei Cas M, Acerbi F, Vetrano IG, Ferroli P, Canavero I, Paroni R, Rifino N, Bersano A, Gatti L.   +12 more
europepmc   +2 more sources

Investigating the association of the plasma lipidomic profile with cognitive performance and genetic risk in the PsyCourse study. [PDF]

Transl Psychiatry
Although lipid biology may play a key role in the pathophysiology of mental health disorders such as schizophrenia (SCZ) and bipolar disorder (BD), the nature of this interplay and how it could shape phenotypic presentation, including cognitive ...
Oraki Kohshour M, Papiol S, Tkachev A, Stekolshchikova E, Adorjan K, Budde M, Heilbronner U, Heilbronner M, Kalman JL, Reich-Erkelenz D, K Schaupp S, Senner F, Vogl T, Wiltfang J, Reininghaus EZ, Juckel G, Dannlowski U, Fallgatter AJ, Spitzer C, Schmauß M, von Hagen M, Falkai P, Khaitovich P, Schulze TG, Schulte EC.   +24 more
europepmc   +2 more sources

Specificity of rat hepatic phosphatidylethanolamine N-methyltransferase for molecular species of diacyl phosphatidylethanolamine.

Journal of Biological Chemistry, 1988
The specificity of phosphatidylethanolamine (PE) N-methyltransferase for molecular species of PE has been investigated. Phosphatidylcholine (PC), synthesized by incubation of [methyl-3H]S-adenosyl-L-methionine with microsomes or pure enzyme (Ridgway, N. D., and Vance, D. E. (1987) J. Biol. Chem.
Neale D. Ridgway, D E Vance
openalex   +4 more sources

Genetic causality of lipidomic and immune cell profiles in ischemic stroke. [PDF]

Front Neurol
BackgroundIschemic stroke (IS) is a global health issue linked to lipid metabolism and immune cell responses. This study uses Mendelian randomization (MR) to identify genetic risk factors for IS subtypes using comprehensive genetic data from lipidomic ...
Chen H, Zheng Z, Cai X, Li S, Chen M, Wu J, He W, Gao F.   +7 more
europepmc   +2 more sources