Results 21 to 30 of about 10,710 (280)

Metabolomic profiling predicts outcome of rituximab therapy in rheumatoid arthritis. [PDF]

, 2016
ObjectiveTo determine whether characterisation of patients' metabolic profiles, utilising nuclear magnetic resonance (NMR) and mass spectrometry (MS), could predict response to rituximab therapy. 23 patients with active, seropositive rheumatoid arthritis
Boyle, David, Guma, Monica, Kavanaugh, Arthur, Lodi, Alessia, Sweeney, Shannon R, Tiziani, Stefano, Wang, Bo   +6 more
core   +2 more sources

DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression

Redox Biology, 2017
Activated platelets generate an eicosanoid proposed to be 8-hydroxy-9,10-dioxolane A3 (DXA3). Herein, we demonstrate that significant amounts of DXA3 are rapidly attached to phosphatidylethanolamine (PE) forming four esterified eicosanoids, 16:0p, 18:0p,
Maceler Aldrovandi, Christine Hinz, Sarah N. Lauder, Helen Podmore, Martin Hornshaw, David A. Slatter, Victoria J. Tyrrell, Stephen R. Clark, Lawrence J. Marnett, Peter W. Collins, Robert C. Murphy, Valerie B. O’Donnell   +11 more
doaj   +1 more source

Fatty liver induction: inverse relationship between hepatic neutral lipid accumulation and dietary polyunsaturated fatty acids in orotic acid-fed rats

Journal of Lipid Research, 1972
The levels of hepatic neutral lipids in the orotic acid-fed rat were inversely related to the dietary levels of polyunsaturated fatty acids, as in the choline-deficient rat.
L.A. Witting
doaj   +1 more source

Plasma Lipidomics Identifies Unique Lipid Signatures and Potential Biomarkers for Patients With Aortic Dissection

Frontiers in Cardiovascular Medicine, 2021
Aortic dissection (AD) is a catastrophic cardiovascular emergency with a poor prognosis, and little preceding symptoms. Abnormal lipid metabolism is closely related to the pathogenesis of AD.
Huang Huang, Guozhu Ye, Song-qing Lai, Hua-xi Zou, Bin Yuan, Qi-cai Wu, Li Wan, Qun Wang, Xue-liang Zhou, Wen-jun Wang, Yuan-ping Cao, Jian-feng Huang, Shi-li Chen, Bi-cheng Yang, Ji-chun Liu   +14 more
doaj   +1 more source

Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

, 2020
A comprehensive characterization of the lipidome from limited starting material remains very challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid chromatography and trapped ion mobility spectrometry (TIMS).
Barsch, A., Brunner, A., Mann, M., Meier, F., Meitei, N., Meyer, S., Schweiger-Hufnagel, U., Sulek, K., Vasilopoulou, C.   +8 more
core   +1 more source

Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients [PDF]

, 2015
There is a clinical need for reliable biomarkers for lung cancer that permit early diagnosis of the disease and provide prediction of histological phenotype.
AG Serrano, AM Fiorenza, Andrew W. Fogarty, CH Oak, D Kong, David A. Barrett, David R. Baldwin, E Wojcik, GL May, H Ulmer, H Yang, Helen L. Barr, J Castro de, J Chee, J Dong, J Liu, JM Poczobutt, K Yanagisawa, K Yang, L Cheng, M Haag, M Hassanein, M Hassanein, M Murphy, MJ Wakelam, MR Wenk, P Brites, R Angelis de, RA Murphy, RA Murphy, RE Smith, RL Keith, RT Sreseli, S Cedres, Srinivasarao Ravipati, WJ Scott, X Gao, X Zeng, Y Guo, YY Tyurina, ZA Fernandis   +40 more
core   +1 more source

Physiology of cold-acclimation in non-diapausing adults of Pyrrhocoris apterus (Heteroptera)

European Journal of Entomology, 2002
Chill tolerance (time of survival at -5°C) increased in non-diapausing (reproducing) adults of Pyrrhocoris apterus after a gradual, 4-week-long decrease in ambient temperature from 25° to 0°C.
Martin ŠLACHTA, Petra BERKOVÁ, Jan VAMBERA, Vladimír KOŠŤÁL   +3 more
doaj   +1 more source

Untargeted UHPLC-TOF/MS Lipidomic Analysis for the Investigation of Egg Yolks after Xylanase Supplementation of the Diet of Laying Hens

Metabolites, 2023
Xylanase supplementation of diets is used to enhance nutrient digestibility in monogastrics which lack necessary enzymes for non-starch polysaccharide degradation.
Artemis Lioupi, Georgios A. Papadopoulos, Domniki Gallou, Christina Virgiliou, Georgios I. Arsenos, Paschalis Fortomaris, Veerle Van Hoeck, Dany Morisset, Georgios Theodoridis   +8 more
doaj   +1 more source

Metabolic profile and root development of Hypericum perforatum L. in vitro roots under stress conditions due to chitosan treatment and culture time [PDF]

, 2016
The responses of Hypericum perforatum root cultures to chitosan elicitation had been investigated through 1H-NMR-based metabolomics associated with morpho-anatomical analyses.
Alessio eValletta, Alfredo eMiccheli, Elisa eBrasili, Fabio eSciubba, Federico eMarini, Gabriella ePasqua, Giulia ePraticò, Maria Enrica eDi Cocco, Maria Enrica eDi Cocco, Noemi eTocci, Valdir eCechinel-Filho, Valdir eCechinel-Filho   +11 more
core   +2 more sources

Dipalmitoleoylphosphoethanolamine as a PP2A Enhancer Obstructs Insulin Signaling by Promoting Ser/Thr Dephosphorylation of Akt

Cellular Physiology and Biochemistry, 2014
Background/Aims: The phospholipid phosphatidylethanolamine is implicated in the regulation of a variety of cellular processes. The present study investigated the effect of phosphatidylethanolamines such as 1,2-diarachidonoyl-sn-glycero-3 ...
Ayako Tsuchiya, Takeshi Kanno, Tomoyuki Nishizaki   +2 more
doaj   +1 more source