Results 91 to 100 of about 31,010 (310)

Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy

open access: yesMovement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik   +8 more
wiley   +1 more source

GLTP-fold interaction with planar phosphatidylcholine surfaces is synergistically stimulated by phosphatidic acid and phosphatidylethanolamine[S]

open access: yesJournal of Lipid Research, 2013
Among amphitropic proteins, human glycolipid transfer protein (GLTP) forms a structurally-unique fold that translocates on/off membranes to specifically transfer glycolipids.
Xiuhong Zhai   +7 more
doaj  

Acetylcholinesterase Inhibition and Antioxidant Activity of DHA‐Disubstituted Phospholipids

open access: yesMolecular Nutrition &Food Research, EarlyView.
1,2‐Di‐DHA‐PC phospholipids in nutraceutical form may cross the blood‐brain barrier and inhibit acetylcholinesterase (AChE) activity, with an efficacy similar to galantamine. This suggests their potential as neuroprotective agents in the treatment of Alzheimer's disease.
Ernestina Garcia‐Quinto   +4 more
wiley   +1 more source

Automated Data Processing Workflows for Non‐Expert Users of NMR Facilities

open access: yesMagnetic Resonance in Chemistry, EarlyView.
Modern NMR spectrometers are typically organized in centralized, ultrahigh‐field facilities with multiple instruments that benefit from shared infrastructure and expertise. The acquisition of NMR experiments goes hand in hand with the analysis of the resulting data.
Armin Afrough   +2 more
wiley   +1 more source

Nrf2‐Mediated Ferroptosis Is Involved in Berberine‐Induced Alleviation of Diabetic Kidney Disease

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Diabetic kidney disease (DKD) is the most common and serious complication of diabetes mellitus. Currently, there is a lack of safe and effective preventive strategies for DKD. The study aimed to explore the preventive effects and potential mechanisms of berberine (BBR) against DKD.
Kun Gao   +6 more
wiley   +1 more source

An efficient synthesis of phosphatidylcholines.

open access: yesJournal of Lipid Research, 1990
This article deals with two of the major steps involved in phospholipid synthesis: the preparation of the optically pure precursors, sn-glycero-3-phosphocholine (GPC) and -ethanolamine, from a convenient lipid source such as egg yolk, and acylation of ...
A Singh
doaj  

Gestational testosterone excess early to mid-pregnancy disrupts maternal lipid homeostasis and activates biosynthesis of phosphoinositides and phosphatidylethanolamines in sheep

open access: yesScientific Reports
Gestational hyperandrogenism is a risk factor for adverse maternal and offspring outcomes with effects likely mediated in part via disruptions in maternal lipid homeostasis.
Nadia Saadat   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy