Results 231 to 240 of about 9,879 (286)

Phosphatidylethanolamines are the Main Lipid Class Altered in Red Blood Cells from Patients with VPS13A Disease/Chorea-Acanthocytosis. [PDF]

Mov Disord
Peikert K, Spranger A, Miltenberger-Miltenyi G, Glaß H, Falkenburger B, Klose C, Tyteca D, Hermann A.   +7 more
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Ketogenic diet impairs NK cell cytotoxic function in colorectal cancer liver metastasis by inducing ferroptosis via suppression of the p62-Keap1-Nrf2 pathway. [PDF]

Redox Biol
Cai R, Meng Y, Ru M, Wang X, Li W, Liu X, Zhuang S, Huang Y, Diao H.   +8 more
europepmc   +1 more source

The Role of One‐Carbon Metabolism in Cancer and Its Therapeutic Significance

MedComm – Oncology, Volume 5, Issue 1, March 2026.
One‐Carbon metabolism in T‐cell activation and tumor competition. T‐cell activation shifts metabolic pathways, promoting anabolic metabolism and bioenergetic capacity. One‐carbon metabolism plays a crucial role in histone and DNA methylation in activated T cells.
Yuting Jiang, Guoliang Zhou, Qian Zhang, Shengtao Zhou   +3 more
wiley   +1 more source

Lipid Subclasses Differentiate Insulin Resistance by Triglyceride-Glucose Index. [PDF]

Metabolites
Naja K, Anwardeen N, Albagha O, Elrayess MA.   +3 more
europepmc   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Cannabinoid Receptors CB1 and CB2 Activation Restores Hippocampal Lipid Profiles and Alleviates Autism-Like Behaviors in Valproic Acid-Induced ASD Rats. [PDF]

CNS Neurosci Ther
Wang H, Zhang M, Yang S, Jiang Y, Wu L, Sun C.   +5 more
europepmc   +1 more source

Lipid Nanoparticles in Drug Delivery: Overcoming Challenges and Unlocking New Frontiers

Small Structures, Volume 7, Issue 3, March 2026.
Lipid nanoparticles (LNPs) have revolutionized nucleic acid delivery, yet challenges in formulation, stability, and targeted efficacy persist. This review explores how advances in microfluidic manufacturing, precision targeting, and endosomal escape are reshaping LNP design.
Jordan Kambanis, Lauren A. Lowe, Jingyi Yao, Zhenxu Yang, Shaoxue Zeng, Ken‐Tye Yong, Ling Zhu, Yi Shen   +7 more
wiley   +1 more source

Innovative Application of a Multifunctional Sucrose-Gelatin Hydrogel Matrix in Desorption Electrospray Ionization-Mass Spectrometry Imaging. [PDF]

Anal Chem
Ziaco M, Vitale GA, Barra G, Marfella B, dell'Isola M, Albiani F, Grazioso A, Giamundo G, Nuzzo G, Manzo E, Gallo C, Castiglia D, Verrillo L, Miano MG, Cristino L, Conte I, d'Ippolito G, Fontana A.   +17 more
europepmc   +1 more source

Trends in Dietary Exosome‐Like Nanoparticles: Preparation, Nutritional Functions, Bioactive Delivery Efficacy, Human Health Effects, and Future Product Development

Small Structures, Volume 7, Issue 3, March 2026.
This graphical abstract summarizes the current advances in dietary exosome‐like nanoparticles (ELNs), highlighting their biogenesis pathways (MVB‐dependent, vacuole‐mediated, and EXPO routes), molecular composition (nucleic acids, lipids, proteins, and bioactive compounds), and major preparation strategies including differential ultracentrifugation ...
Nidesha Randeni, Jinhai Luo, Min‐Hsiung Pan, Baojun Xu   +3 more
wiley   +1 more source