Plant‐derived oleosome; structural morphology, extraction, oleosome‐membrane proteins extraction, fabrication techniques, and cutting‐edge food and pharmaceutical applications. ABSTRACT Oleosomes are spherical subcellular organelles comprising triacylglycerols and sterol esters (lipid core) surrounded by a specialized monolayer membrane, composed of ...
Zafarullah Muhammad +7 more
wiley +1 more source
Editorial: Exploring 'omic' biomarkers in animal production and reproduction. [PDF]
Aponte PM +2 more
europepmc +1 more source
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
Editorial: Integrated diagnostics and biomarker discovery in endocrinology and biomedical sciences, volume II. [PDF]
Park K +7 more
europepmc +1 more source
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Phosphatidylethanolamines are the Main Lipid Class Altered in Red Blood Cells from Patients with VPS13A Disease/Chorea-Acanthocytosis. [PDF]
Peikert K +7 more
europepmc +1 more source
Sex‐specific acceleration of Alzheimer's pathogenesis by chronic sleep‐deprivation
Abstract INTRODUCTION Sleep impairments likely contribute to Alzheimer's pathology, though specific contributions to disease progression are incompletely understood. We propose that autophagic impairment is associated with chronic sleep disruption and examine how sleep loss and stress influence disease development, including having impacts on ...
Darcy Wear +5 more
wiley +1 more source
Ketogenic diet impairs NK cell cytotoxic function in colorectal cancer liver metastasis by inducing ferroptosis via suppression of the p62-Keap1-Nrf2 pathway. [PDF]
Cai R +8 more
europepmc +1 more source
GPR183‐mediated activation of PI3K is a potential biomarker for immunotherapy in lung cancer
Anti‐PD1 treatment and PI3Kγ inhibition had remarkable therapeutic performance on CD4+ Tcm and CD4+ Tn in lung cancer through potential regulation of PI3K pathway with participation of GPR183. Abstract Background As one of commonly used immune checkpoint inhibition therapies, PD1 monoclonal antibodies exhibit a promising cancer immunotherapy approach ...
Ling Ye +9 more
wiley +1 more source
Innovative Application of a Multifunctional Sucrose-Gelatin Hydrogel Matrix in Desorption Electrospray Ionization-Mass Spectrometry Imaging. [PDF]
Ziaco M +17 more
europepmc +1 more source

