Results 51 to 60 of about 8,364 (275)

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

open access: yesHepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol   +22 more
wiley   +1 more source

Distribution of the predominant inner and outer membrane phosphatidylethanolamines and phosphatidylglycerols in planktonic and biofilms Pseudomonas aeruginosa (results are given with 95% confidence interval). [PDF]

open access: yes, 2014
Values in straight correspond to the internal membrane - Values in italic correspond to the outer membrane.*Total number of C: Number of equivalent unsaturation – R and R' represent the fatty acid moiety with no indication of their position.Note that a ...
Stéphane Alexandre (200620)   +6 more
core   +1 more source

Phosphatidylethanolamine Metabolism in Health and Disease [PDF]

open access: yes, 2016
Phosphatidylethanolamine (PE) is the second most abundant glycerophospholipid in eukaryotic cells. The existence of four only partially redundant biochemical pathways that produce PE, highlights the importance of this essential phospholipid. The CDP-ethanolamine and phosphatidylserine decarboxylase pathways occur in different subcellular compartments ...
Elizabeth, Calzada   +2 more
openaire   +2 more sources

Additional file 2 of Exploring preconception signatures of metabolites in mothers with gestational diabetes mellitus using a non-targeted approach [PDF]

open access: yes, 2023
Additional file 2: Tab. S2. The intra-coefficient of variation (CV) among all identified phosphatidylethanolamines in our study after eight attempts of quality ...
Ximeng Wang (793633)   +9 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

N-acyl phosphatidylethanolamines affect the lateral distribution of cholesterol in membranes [PDF]

open access: yes, 2005
N-Acyl phosphatidylethanolamines are negatively charged phospholipids, which are naturally occurring albeit at low abundance. In this study, we have examined how the amide-linked acyl chain affected the membrane behavior of the N-acyl-1-palmitoyl-2 ...
Slotte, J. Peter   +6 more
core   +1 more source

Synthetic Phosphatidylethanolamines as Renin Inhibitors

open access: yesExperimental Biology and Medicine, 1977
SummaryAnti-renin and hypotensive effects of synthetic PEs were examined.(i) Eighteen PEs including optical isomers were newly synthesized. Arachidonic acid, linolenic acid, and stearic acid were substituted at the positions of β, γ, or both. Natural PE was extracted from porcine kidney, and the lyso form was prepared by treatment of phospholipase A ...
M, Miyazaki, K, Yamamoto
openaire   +2 more sources

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Calorimetric and spectroscopic studies of the polymorphic phase behavior of a homologous series of n-saturated 1,2-diacyl phosphatidylethanolamines [PDF]

open access: yes, 1993
The polymorphic phase behavior of a homologous series of n-saturated 1,2-diacyl phosphatidylethanolamines was investigated by differential scanning calorimetry, 31P-nuclear magnetic resonance, and Fourier transform infrared spectroscopy.
Lewis, R.N., McElhaney, R.N.
core   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

open access: yesAdvanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan   +10 more
wiley   +1 more source

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